528587-94-2

Basic information

• Product Name: (1S,2R)-1-(3-fluorophenyl)-2-[(S)-1-hydroxypropyl]-N,N-diethylcyclopropanecarboxamide
• Synonyms: (1S,2R)-1-(3-fluorophenyl)-2-[(S)-1-hydroxypropyl]-N,N-diethylcyclopropanecarboxamide
• CAS NO: 528587-94-2
• Molecular Weight: 293.381
• Mol File: 528587-94-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S,2R)-1-(3-fluorophenyl)-2-[(S)-1-hydroxypropyl]-N,N-diethylcyclopropanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1-(3-fluorophenyl)-2-[(S)-1-hydroxypropyl]-N,N-diethylcyclopropanecarboxamide(528587-94-2)
• EPA Substance Registry System: (1S,2R)-1-(3-fluorophenyl)-2-[(S)-1-hydroxypropyl]-N,N-diethylcyclopropanecarboxamide(528587-94-2)

Safety Data

• Hazardous Substances Data: 528587-94-2(Hazardous Substances Data)

Upstream product

• 528587-78-2 (1S,2R)-1-(3-fluorophenyl)-2-(hydroxymethyl)-N,N-diethylcyclopropanecarboxamide 
• 528587-70-4 (1S,5R)-2-oxo-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexane 
• 501-00-8 3-fluorophenylacetonitrile 
• 925-90-6 ethylmagnesium bromide 
• 528587-86-2 (1S,2R)-1-(3-fluorophenyl)-2-formyl-N,N-diethylcyclopropanecarboxamide 

Downstream Products

• 528588-02-5 (1S,2R)-1-(3-fluorophenyl)-2-[(S)-1-azidopropyl]-N,N-diethylcyclopropanecarboxamide 
• 528588-18-3 (1S,4S,5R)-2-oxo-4-ethyl-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexane 

Relevant articles and documents

Synthesis of derivatives of (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC) modified at the 1-aromatic moiety as novel NMDA receptor antagonists: The aromatic group is essential for the activity

(1S,2R)-1-Phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropanecarboxamide (PPDC, 4a), which is a conformationally restricted analogue of antidepressant milnacipran [(±)-1], is a new class of potent noncompetitive NMDA receptor antagonists. A series of PPD