5289-18-9

Basic information

• Product Name: 4-benzylidene-2-phenylisoxazolidine-3,5-dione
• Synonyms: 4-benzylidene-2-phenylisoxazolidine-3,5-dione
• CAS NO: 5289-18-9
• Molecular Weight: 265.268
• Mol File: 5289-18-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-benzylidene-2-phenylisoxazolidine-3,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzylidene-2-phenylisoxazolidine-3,5-dione(5289-18-9)
• EPA Substance Registry System: 4-benzylidene-2-phenylisoxazolidine-3,5-dione(5289-18-9)

Safety Data

• Hazardous Substances Data: 5289-18-9(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 5305-00-0 2-phenylisoxazolidine-3,5-dione 
• 100-65-2 N-Phenylhydroxylamine 

Downstream Products

• 110862-45-8 1-<2-(1,3-dioxolan-2-yl)ethyl>-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1H-pyrrole-3-carboxamide 
• 70451-27-3 2-methyl-N,4,5-triphenyl-1H-pyrrole-3-carboxamide 

Relevant articles and documents

Regioselective Decarboxylative Cycloaddition Route to Fully Substituted 3-CF3-Pyrazoles from Nitrilimines and Isoxazolidinediones

1,4-Diaryl-5-carboxamido substituted 3-trifluoromethylpyrazoles are obtained with exclusive regioselectivity under transition-metal-free conditions. This decarboxylative [3+2] cycloaddition protocol was enabled by employing trifluoromethyl nitrilimines as 1,3-dipoles, and isoxazolidinediones as CO2-masked alkynyl dipolarophiles. The applicability of this method is further manifested by its compatibility with difluoromethyl, alkyl, aryl, and heteroaryl nitrilimines, as well as the preparation of 4-carboxylic amido analogue of drug Celebrex. (Figure presented.).

4-benzylidene -2-aryl isoxazolidine -3,5- diketone and preparation method thereof

The invention provides 4 -benzyl - 2 2-aryl isoxazolidin- 33335-dione and a preparation method, thereof, and the molecule has the formula (I) in the structure, Ar1 AND Ar2 A method. of synthesizing 4 -arylisoxazolidine - 3333,5-dione