52938-97-3

Basic information

• Product Name: 5-PHENYL-2-FUROIC ACID
• Synonyms: AKOS B025035;AKOS BAR-0049;5-PHENYL-FURAN-2-CARBOXYLIC ACID;5-PHENYL-2-FURANCARBOXYLIC ACID;5-PHENYL-2-FUROIC ACID;ART-CHEM-BB B025035;ASISCHEM V38284;LABOTEST-BB LT00569128
• CAS NO: 52938-97-3
• Molecular Formula: C₁₁H₈O₃
• Molecular Weight: 188.18
• Product Categories: Building Blocks;Furans;Heterocyclic Building Blocks
• Mol File: 52938-97-3.mol
• Article Data: 36

Chemical Properties

• Melting Point: 150-154 °C(lit.)
• Boiling Point: 368.2 °C at 760 mmHg
• Flash Point: 176.5 °C
• Appearance: /
• Density: 1.254 g/cm³
• Vapor Pressure: 4.54E-06mmHg at 25°C
• Refractive Index: 1.581
• Storage Temp.: 2-8°C
• PKA: 3.15±0.10(Predicted)
• CAS DataBase Reference: 5-PHENYL-2-FUROIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENYL-2-FUROIC ACID(52938-97-3)
• EPA Substance Registry System: 5-PHENYL-2-FUROIC ACID(52938-97-3)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 52938-97-3(Hazardous Substances Data)

Usage

General Description

5-Phenyl-2-furoic acid is a chemical compound with the molecular formula C11H8O3. It is a phenyl-substituted derivative of furan-2-carboxylic acid, and is also known as 5-phenylfuran-2-carboxylic acid. 5-PHENYL-2-FUROIC ACID is often used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It is a white to off-white crystalline powder, and is slightly soluble in water but more soluble in organic solvents such as ethanol and ethyl acetate. 5-Phenyl-2-furoic acid has potential applications in the development of drugs and agrochemicals, and is also used as a building block in organic synthesis.

InChI:InChI=1/C11H8O3/c12-11(13)10-7-6-9(14-10)8-4-2-1-3-5-8/h1-7H,(H,12,13)

Upstream product

• 13803-39-9 5-phenylfuran-2-carbaldehyde 
• 585-70-6 5-bromo-furan-2-carboxylic acid 
• 960-16-7 tributylphenylstannane 
• 595-90-4 tetraphenyltin(IV) 
• 88-14-2 2-furanoic acid 
• 2527-99-3 methyl 5-bromo-2-furoate 
• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 98-80-6 phenylboronic acid 
• 108-86-1 bromobenzene 
• 27329-70-0 5-formylfurane-2-boronic acid 
• 62-53-3 aniline 
• 143-66-8 sodium tetraphenyl borate 
• 52939-03-4 5-phenylfuran-2-carboxylic acid methyl ester 
• 1124-19-2 phenyltin trichloride 

Downstream Products

• 80174-05-6 5-phenyl-2-furoyl azide 
• 1354698-21-7 N-5-phenyl-2-furoyl-1H-pyrazole 
• 1354698-32-0 N-5-phenyl-2-furoyl-1H-1,2,4-triazole 
• 1403473-77-7 N-{3-[3-(tert-butoxycarbonylamino)benzyl]-2,4-dioxoimidazolidin-1-yl}-5-phenyl-2-furamide 
• 1403473-09-5 N-[3-(3-aminobenzyl)-2,4-dioxoimidazolidin-1-yl]-5-phenyl-2-furamide hydrochloride 
• 1403473-71-1 5-phenyl-N-(2,4-dioxoimidazolidin-1-yl)-2-furamide 
• 92972-89-9 [(5-Phenyl-furan-2-carbonyl)-amino]-acetic acid ethyl ester 
• 52939-03-4 5-phenylfuran-2-carboxylic acid methyl ester 
• 60336-05-2 Ethyl 5-phenylfuran-2-carboxylate 

Relevant articles and documents

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

Thiazolidin-2-cyanamides derivatives as novel potent Escherichia coli β-glucuronidase inhibitors and their structure–inhibitory activity relationships

Gut microbial β-glucuronidases have the ability to deconjugate glucuronides of some drugs, thus have been considered as an important drug target to alleviate the drug metabolites-induced gastrointestinal toxicity. In this study, thiazolidin-2-cyanamide de

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

The α7 nicotinic acetylcholine receptor (nAChR) silent agonists, able to induce receptor desensitization and promote the α7 metabotropic function, are emerging as new promising therapeutic anti-inflammatory agents. Herein, we report the structure–activity