52939-61-4

Basic information

• Product Name: 4-PROPYL-1,6-HEPTADIEN-4-OL
• Synonyms: 4-PROPYL-1,6-HEPTADIEN-4-OL
• CAS NO: 52939-61-4
• Molecular Formula: C₁₀H₁₈O
• Molecular Weight: 154.25
• Mol File: 52939-61-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 222.5°Cat760mmHg
• Flash Point: 83.6°C
• Appearance: /
• Density: 0.85g/cm³
• Vapor Pressure: 0.0207mmHg at 25°C
• Refractive Index: 1.456
• PKA: 14.97±0.29(Predicted)
• CAS DataBase Reference: 4-PROPYL-1,6-HEPTADIEN-4-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PROPYL-1,6-HEPTADIEN-4-OL(52939-61-4)
• EPA Substance Registry System: 4-PROPYL-1,6-HEPTADIEN-4-OL(52939-61-4)

Safety Data

• Hazardous Substances Data: 52939-61-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H18O/c1-4-7-10(11,8-5-2)9-6-3/h4-5,11H,1-2,6-9H2,3H3

Upstream product

• 106-31-0 butanoic acid anhydride 
• 556-56-9 allyl iodid 
• 105-54-4 butanoic acid ethyl ester 
• 18854-66-5 tris(allyl)aluminum 
• 623-42-7 butanoic acid methyl ester 
• 4635-59-0 4-Chlorobutanoyl chloride 
• 1730-25-2 allylmagnesium bromide 
• 141-75-3 butyryl chloride 
• 107-05-1 3-chloroprop-1-ene 
• 106-95-6 allyl bromide 
• 817-76-5 2-chloropropyl methyl ester 

Downstream Products

• 17312-72-0 4,4-dipropylheptane 
• 124-38-9 carbon dioxide 
• 64-19-7 acetic acid 
• 107-92-6 butyric acid 

Relevant articles and documents

An efficient of Grignard-type procedure for the preparation of gem-diallylated compound

An efficient and a new procedure for the conversion of various carboxylic acid derivatives into the corresponding gem-diallylated compound under mild reaction condition has been developed. The triallylaluminum mediated Grignard-type addition of carboxylic acid derivative was utilized as a key operation to affect the transformation. The procedure is operationally simple, giving good to excellent product yields for a broad range of substrates. The chemoselectivity and regioselectivity of triallylaluminum were also demonstrated.

Metal zinc-promoted gem-bisallylation of acid chlorides with allyl chlorides in the presence of chlorotrimethylsilane

Treatment of acid chlorides (2) with allyl chlorides (1) in the presence of zinc dust and a catalytic amount of chlorotrimethylsilane (TMSCl) in THF brought about highly facile and effective coupling to give the corresponding gem-bisallylation products, 4-hydroxy-penta-1,6-dienes (3), in good to excellent yields. These reactions are assumed to proceed through allylzinc intermediates generated in situ.

3-Alkyl-3-hydroxyglutaric acids: A new class of hypocholesterolemic HMG CoA reductase inhibitors. 1

Derivatives of 3-hydroxy-3-methylglutaric acid (HMG), a portion of the substrate for HMG CoA reductase, were prepared and tested for their inhibitory action against rat liver HMG CoA reductase and for their hypocholesterolemic activity. Structure-dependent competitive inhibition was observed. Optimal structures had a freee dicarboxylic acid with an alkyl group of 13-16 carbons at position 3. 3-n-Pentadecyl-3-hydroxyglutaric acid (IC50 = 50 μM) reduced serum cholesterol in the Triton-treated rat and HMG CoA reductase activity in the 20,25-diazacholesterol-treated rat.