52942-39-9

Basic information

• Product Name: 6,8-dibromo-3-(4-bromo-phenyl)-benzo[e][1,3]oxazine-2,4-dione
• Synonyms: 6,8-dibromo-3-(4-bromo-phenyl)-benzo[e][1,3]oxazine-2,4-dione
• CAS NO: 52942-39-9
• Molecular Weight: 475.919
• Mol File: 52942-39-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6,8-dibromo-3-(4-bromo-phenyl)-benzo[e][1,3]oxazine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6,8-dibromo-3-(4-bromo-phenyl)-benzo[e][1,3]oxazine-2,4-dione(52942-39-9)
• EPA Substance Registry System: 6,8-dibromo-3-(4-bromo-phenyl)-benzo[e][1,3]oxazine-2,4-dione(52942-39-9)

Safety Data

• Hazardous Substances Data: 52942-39-9(Hazardous Substances Data)

Upstream product

• 106-40-1 4-bromo-aniline 
• 3147-55-5 3,5-dibromosalicylic acid 
• 87-10-5 3,5,4'-tribromosalicylanilide 
• 541-41-3 chloroformic acid ethyl ester 

Relevant articles and documents

Relationships between the chemical structure of antimycobacterial substances and their activity against atypical strains. Part 14: 3-Aryl-6,8-dihalogeno-2H-1,3-benzoxazine-2,4(3H)-diones)

A set of eight derivatives of 6,8-dichloro-3-phenyl-2H-benzoxazine-2,4(3H)-dione and nine derivatives of 6,8-dibromo-3-phenyl-2H-1,3-benzoxazine-2,4(3H)-dione, substituted on the phenyl ring, was prepared by the reaction of the corresponding salicylanilides with ethyl chloroformate. The compounds were evaluated in vitro for antimycobacterial activity against Mycobacterium tuberculosis, Mycobacterium kansasii, and Mycobacterium avium. Their activity increases with increasing hydrophobicity and electron-withdrawing ability of the substituents on the phenyl ring.

SUBSTITUTED 3-PHENYL-1,3-BENZOXAZINE-2,4-DIONES AND THEIR

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