52944-84-0Relevant articles and documents
Iridium(III)-Catalyzed C H Amidation of Arylphosphoryls Leading to a P-Stereogenic Center
Gwon, Donghyeon,Lee, Donggun,Kim, Jiyu,Park, Sehoon,Chang, Sukbok
, p. 12421 - 12425 (2014)
Direct C H amidation of arylphosphoryl compounds has been developed by using an IrIIIcatalyst system under mild conditions. A wide range of substrates could be employed with high functional-group tolerance. This procedure was successfully applied for the first time to the asymmetric reaction giving rise to a P-chirogenic center with a high diastereomeric ratio of up to 19:1 (90 % de).