530145-21-2

Basic information

• Product Name: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate
• Synonyms: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate
• CAS NO: 530145-21-2
• Molecular Weight: 284.312
• Mol File: 530145-21-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate(530145-21-2)
• EPA Substance Registry System: methyl 4-(2-(benzyloxy)-2-oxoethyl)benzoate(530145-21-2)

Safety Data

• Hazardous Substances Data: 530145-21-2(Hazardous Substances Data)

Upstream product

• 18153-53-2 methyl 4-(N,N-dimethylaminomethyl)benzoate 
• 201230-82-2 carbon monoxide 
• 100-51-6 benzyl alcohol 

Downstream Products

• 22744-12-3 [4-(methoxycarbonyl)phenyl]acetic acid 
• 1354804-45-7 4-{2-[9-(3-fluorobenzyl)-5,6,8,9-tetrahydro-7H-pyrido[4',3':4,5]pyrrolo[2,3-b]pyridin-7-yl]-2-oxoethyl}benzoic acid 

Relevant articles and documents

Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation

An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.