53016-31-2

Basic information

• Product Name: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)
• Synonyms: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE);,10-alpha,13-alpha,14-beta)-;18,19-dinorpregn-4-en-20-yn-3-one,13-ethyl-17-hydroxy-,oxime,(8-alpha,9-beta;levonorgestreloxime; 17-Deacetylnorgestimate;(17a)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one Oxime;18-Methylnorethindrone oxime;BRN 4202099
• CAS NO: 53016-31-2
• Molecular Formula: C21H29NO2
• Molecular Weight: 327.465
• Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Steroids
• Mol File: 53016-31-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 107-109°C
• Boiling Point: 491.9°Cat760mmHg
• Flash Point: 327.1°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 9.76E-12mmHg at 25°C
• Refractive Index: 1.633
• Storage Temp.: Refrigerator
• PKA: 12.22±0.60(Predicted)
• CAS DataBase Reference: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)(CAS DataBase Reference)
• NIST Chemistry Reference: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)(53016-31-2)
• EPA Substance Registry System: DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)(53016-31-2)

Safety Data

• Hazardous Substances Data: 53016-31-2(Hazardous Substances Data)

Usage

Description

DEACETYLNORGESTIMATE (25 MG) ((E)AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) is a metabolite of Norgestimate, a synthetic progestin used in contraceptive medications. It is a white solid substance that plays a crucial role in birth control for women.

Uses

Used in Pharmaceutical Industry:
DEACETYLNORGESTIMATE (25 MG) ((E)AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) is used as an active ingredient in contraceptive medications for women. It is utilized to prevent pregnancies by suppressing ovulation, altering the cervical mucus, and affecting the endometrium.
Used in Birth Control Patch Development:
In the development of birth control transdermal patches like Ortho Evra, DEACETYLNORGESTIMATE (25 MG) ((E)AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) is used as the active metabolite of norelgestromin. The patch offers convenience and efficacy, with a 99% success rate when used appropriately. It provides ovarian suppression and cycle control, making it a popular choice for women seeking an alternative to oral contraceptives.
Used in Combination with Ethinylestradiol:
DEACETYLNORGESTIMATE (25 MG) ((E)AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) is used in combination with ethinylestradiol, an estrogen component, to enhance the contraceptive effectiveness of the medication. This combination helps in achieving a higher rate of preventing pregnancies and maintaining a similar tolerability profile as other leading oral contraceptives.
Used in Research and Development:
DEACETYLNORGESTIMATE (25 MG) ((E)AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE) is also used in research and development for potential applications in various fields, including pharmaceuticals, due to its unique chemical properties and role as a metabolite of Norgestimate.

Originator

Johnson & Johnson (USA)

InChI:InChI=1/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/m0/s1