53018-27-2

Basic information

• Product Name: Cyclohexanemethanol, 3-methyl-
• CAS NO: 53018-27-2
• Molecular Formula: C8H16O
• Molecular Weight: 128.214
• Mol File: 53018-27-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Cyclohexanemethanol, 3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanemethanol, 3-methyl-(53018-27-2)
• EPA Substance Registry System: Cyclohexanemethanol, 3-methyl-(53018-27-2)

Safety Data

• Hazardous Substances Data: 53018-27-2(Hazardous Substances Data)

Upstream product

• 13293-59-9 (+/-)-cis-3-methyl-cyclohexanecarboxylic acid 
• 80729-05-1 3-methylcyclohex-2-en-1-ylmethanol 
• 201230-82-2 carbon monoxide 
• 591-47-9 4-methylcyclohexene 
• 1421022-53-8 bis(3-methylcyclohexylmethyl)cyclohexane-1,3-dicarboxylate 
• 13293-59-9 3-methylcyclohexanecarboxylic acid 
• 3070-53-9 1,6-heptadiene 
• 75-24-1 trimethylaluminum 
• 67-56-1 methanol 
• 82166-21-0 methyl cyclohexane 
• 99-04-7 m-Toluic acid 

Downstream Products

• 1421022-52-7 bis(3-methylcyclohexylmethyl) isophthalate 
• 148258-56-4 1-bromomethyl-3-methyl-cyclohexane 

Relevant articles and documents

Iridium-Catalyzed Domino Hydroformylation/Hydrogenation of Olefins to Alcohols: Synergy of Two Ligands

A novel one-pot iridium-catalyzed domino hydroxymethylation of olefins, which relies on using two different ligands at the same time, is reported. DFT computation reveals different activities for the individual hydroformylation and hydrogenation steps in the presence of mono- and bidentate ligands. Whereas bidentate ligands have higher hydrogenation activity, monodentate ligands show higher hydroformylation activity. Accordingly, a catalyst system is introduced that uses dual ligands in the whole domino process. Control experiments show that the overall selectivity is kinetically controlled. Both computation and experiment explain the function of the two optimized ligands during the domino process.

PROCESS FOR THE PREPARATION OF 1,3-CYCLOHEXANEDIMETHANOL FROM ISOPHTHALIC ACID

Disclosed is a process for the preparation of 1,3-cyclohexanedimethanol from isophthalic acid. Isophthalic acid is esterified with (3-methylcyclohexyl)methanol and the isophthalate ester hydrogenated to 1,3-cyclohexanedimethanol in a 2-stage process. The (3-methylcyclohexyl)methanol that is formed during the hydrogenation step is recycled to the esterification reaction. Also disclosed is a method for purifying and recovering the 1,3-cyclohexanedimethanol product.

ANTIALLERGY AND ANTIINFLAMMATORY BENZOXAZOLINONES

This invention relates to certain benzoxazolinones which inhibit lipoxygenase and/or cyclooxygenase enzymes. Such compounds are useful in inhibiting such enzymes, per se, and are useful in treating allergic and inflammatory conditions in a mammal. This in