53074-09-2

Basic information

• Product Name: 2-hydrazino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidin-4(3H)-one
• Synonyms: 2-hydrazino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidin-4(3H)-one
• CAS NO: 53074-09-2
• Molecular Weight: 236.297
• Mol File: 53074-09-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydrazino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydrazino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidin-4(3H)-one(53074-09-2)
• EPA Substance Registry System: 2-hydrazino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidin-4(3H)-one(53074-09-2)

Safety Data

• Hazardous Substances Data: 53074-09-2(Hazardous Substances Data)

Upstream product

• 105544-62-5 N-(3-carboethoxy-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-N-thiourea 

Downstream Products

• 143770-09-6 2-azido-4-<4-chlorophenyl>amino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-08-5 2-azido-4-<4-methoxyphenyl>amino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-07-4 2-azido-4-amino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-06-3 2-azido-4-phenylamino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-28-9 2-amino-4-<4-methoxyphenyl>amino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-29-0 2-amino-4-<4-chlorophenyl>amino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-27-8 2-amino-4-<4-methylphenyl>amino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-26-7 2-amino-4-phenylamino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 848667-30-1 4-(p-methoxyphenyl)-1-(4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)thiosemicarbazide 
• 848667-32-3 4-(p-ethoxycarbonylphenyl)-1-(4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)thiosemicarbazide 
• 302949-25-3 1-(4-Oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)-4-phenylthiosemicarbazide 

Relevant articles and documents

Studies on synthesis and reactions of some new five and six-membered heterocycles bearing 5,6,7,8-tetrahydrobenzo[b]thieno[2,3-d]pyrimidin-4(3H)-ones skeleton

Thienopyrimidine derivatives are well-known in various pharmaceutical and biomedical domains. In this work, a series of efficacious and novel strategies for the synthesis of thienopyrimidines starting from 2-amino-3-carboethoxy-4,5,6,7-tetrahydrobenzo[b]thiophene has been developed. The regioselectivity of these synthetic strategies was investigated using density functional theory computation and spectroscopic analysis. In addition, the chemical structures of the new thienopyrimidines and their reaction mechanisms, as well as the biological activity of selected compounds were studied.