5308-51-0

Basic information

• Product Name: 2,3-Butanedione, 1-bromo-
• Synonyms: 2,3-Butanedione, 1-bromo-;1-BroMobutane-2,3-dione;1-Bromo-2,3-butanedione;Bromobiacetyl;1-Bromobutane-2,3-dione98%
• CAS NO: 5308-51-0
• Molecular Formula: C₄H₅BrO₂
• Molecular Weight: 164.99
• Mol File: 5308-51-0.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 148℃
• Flash Point: 65℃
• Appearance: /
• Density: 1.617
• CAS DataBase Reference: 2,3-Butanedione, 1-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Butanedione, 1-bromo-(5308-51-0)
• EPA Substance Registry System: 2,3-Butanedione, 1-bromo-(5308-51-0)

Safety Data

• Hazardous Substances Data: 5308-51-0(Hazardous Substances Data)

Usage

General Description

2,3-Butanedione, 1-bromo- is a chemical compound that consists of a butanedione molecule with a bromine atom attached to the first carbon atom. It is a yellow liquid with a strong, pungent odor and is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, and organic synthesis. It is also used as a reagent in chemical reactions and as a solvent for various organic compounds. However, it is important to handle 2,3-Butanedione, 1-bromo- with caution as it is considered to be a reactive and potentially hazardous chemical.

Upstream product

• 431-03-8 dimethylglyoxal 
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Downstream Products

• 317377-32-5 1-(2'-methylthiazol-4'-yl)ethanone hydrobromide 
• 2840-10-0 1-bromobutane-2,3-dione-3-oxime 
• 2840-10-0 1-bromo-butane-2,3-dione 3-(Z)-oxime 
• 602313-68-8 2-acetylimidazo[1,2-a]pyridine 
• 101258-16-6 1-(2-amino-1,3-thiazol-4-yl)ethanone 
• 5320-95-6 2-(bromomethyl)-3-methyl-quinoxaline 
• 1338371-55-3 1-[3-amino-4-(4-methoxyphenylazo)-5-morpholinothiophen-2-yl]ethanone 
• 1023742-10-0 ethyl 5-acetyl-2-(2-fluoro-4-iodophenylamino)-1H-pyrrole-3-carboxylate 
• 1023742-63-3 ethyl 5-acetyl-2-((4-bromo-2-fluorophenyl)amino)-1H-pyrrole-3-carboxylate 

Relevant articles and documents

Therapeutic compounds

The invention provides a compound of formula I: or a salt thereof, wherein R2-R4 and p have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as ant

Optimisation of conoidin A, a peroxiredoxin inhibitor

Lead optimisation: Interest in the inhibition of peroxiredoxin has been revitalised by their recently identified role in signalling cascades. Here, the synthesis and analysis of novel analogues of the peroxiredoxin inhibitor conoidin A is described. Computational methods are used to rationalise the generated SAR data. These studies lead to a proposed binding mode for this class of compounds that will aid the design of second generation inhibitors. (Figure Presented)

Stereoselectivity in the formation of tris-diimine complexes of Fe(ii), Ru(ii), and Os(ii) with a C2-symmetric chiral derivative of 2,2′-bipyridine

A C2-symmetric enantiopure 4,5-bis(pinene)-2, 2′-bipyridine ligand (-)-L was used to investigate the diastereoselectivity in the formation of [ML3]2+ coordination species (M = Fe(ii), Ru(ii), Os(ii), Zn(ii), Cd(ii), Cu(ii), Ni(ii)), and [ML2Cl2] (M = Ru(ii), Os(ii)). The X-ray structures of the [ML3]2+ complexes were determined for Δ-[FeL3](PF6)2, Δ-[RuL 3](PF6)2, Λ-[RuL3](PF 6)2, Δ-[OsL3](PF6) 2, and Λ-[OsL3](TfO)2. All of these compounds were also characterized by NMR, CD and UV/VIS absorption spectroscopy. The [FeL3]2+ diastereoisomers were studied in equilibrated solutions at various temperatures and in several solvents. The [RuL3]2+ complexes, which are thermally stable up to 200 °C, were photochemically equilibrated. The Royal Society of Chemistry 2006.