53173-72-1

Basic information

• Product Name: 3,5-BIS(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPYL)IODOBENZENE
• Synonyms: 3,5-BIS(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPYL)IODOBENZENE;3,5-BIS(2-HYDROXYHEXAFLUOROISOPROPYL)IODOBENZENE;1,3-Bis[perfluoro(2-hydroxyprop-2-yl)]-5-iodobenzene, 1,3-Bis(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)-5-iodobenzene;2,2'-(5-Iodobenzene-1,3-diyl)bis(1,1,1,3,3,3-hexafluoropropan-2-ol)
• CAS NO: 53173-72-1
• Molecular Formula: C₁₂H₅F₁₂IO₂
• Molecular Weight: 536.05
• Mol File: 53173-72-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 80-81
• Flash Point: 173.1°C
• Appearance: /
• Density: 1.967g/cm³
• Refractive Index: 1.4385
• PKA: 8.26±0.19(Predicted)
• CAS DataBase Reference: 3,5-BIS(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPYL)IODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-BIS(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPYL)IODOBENZENE(53173-72-1)
• EPA Substance Registry System: 3,5-BIS(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPYL)IODOBENZENE(53173-72-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 53173-72-1(Hazardous Substances Data)

Usage

General Description

"3,5-BIS(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPYL)IODOBENZENE" is a synthetic chemical compound that has fluorine, hydrogen, oxygen, iodine, and carbon atoms. This chemical is known for its complex structure and it is often utilized in advanced chemical research and experiments due to its unique properties. There is a lack of widely accessible information regarding its specific uses and hazards, which suggests that it's predominantly used in specialized scientific contexts, likely within the realm of organic chemistry or material science. Its distinct structure signifies that it belongs to the group of halogenated hydrocarbons, a class of compounds known for their diverse range of uses from refrigerants to propellants.

Upstream product

• 802-93-7 1,3-bis-(1-hydroxy-1-trifluoromethyl-2,2,2-trifluoroethyl)-benzene 
• 71-43-2 benzene 

Downstream Products

• 53896-20-1 3,5-bis<1-methoxy-2,2,2-trifluoro-1-(trifluoromethyl)ethyl>iodobenzene 
• 136365-60-1 <(5-(Trifluoroethenyl)-1,3-phenylene)bis<2,2,2-trifluoro-1-(trifluoromethyl)ethylidene>oxy>bis 
• 90780-28-2 1,3-bis(2-methoxyhexafluoro-2-propyl)-5-(2-hydroxyhexafluoro2-propyl)benzene 
• 14860-85-6 1,3,5-tris(2-hydroxyhexafluoro-2-propyl)benzene 
• 53896-18-7 1,3-bis<1-methoxy-2,2,2-trifluoro-1-(trifluoromethyl)ethyl>benzene 

Relevant articles and documents

Bifunctional Fluoroalcohol Catalysts Enabled Sustainable Synthesis of Poly(amino acid)s?

A series of novel bifunctional single-molecule hydrogen-bonding organocatalysts based on fluorinated tertiary alcohol were synthesized to mediate the metal-free polymerization of α-amino acid N-carboxyanhydride (NCA) monomer. Through the screening of catalysts, the polymerization catalyzed by the preferred bifunctional fluoroalcohol catalyst proceeded in a fast and controlled manner, affording high molecular weight polypeptide up to 35.2 × 104 Da with relatively narrow molecular weight distribution (? 1.20). A phenomenon of self-accelerating effect of polymerization induced by α-helical structure of polypeptides was observed, and a possible polymerization pathway has been discussed.

Syntheses and lipophilicities of tetraarylborate ions substituted with many trifluoromethyl groups

Syntheses were investigated using various tetraarylborate ions with a large number of trifluoromethyl groups: tetrakisborate; tetrakisborate; tetrakisborate; and tetrakisborate ions.The preparation of Grignard reagents and the subsequent reaction with boron trifluoride etherate are importantsteps for a higher yield and easier isolation of the product.Sodium- and tetramethylammonium salts of these borate ions are soluble in halocarbon solvents such as dichloromethane, chloroform and 1,2-dibromotetrafluoroethane.

PERFLUOROALKYLATION OF BENZENE DERIVATIVES. AN IMPROVED SYNTHESIS OF 1,3-BIS(2-HYDROXYHEXAFLUORO-2-PROPYL)-5-(PERFLUORO-n-ALKYL)BENZENES

A three-step high yield synthesis of various 1,3-bis(2-hydroxyhexafluoro-2-propyl)-5-perfluoro-n-alkyl) benzenes is described.Significant improvements in the iodination and perfluoro-alkylation of a perfluoroalkylbenzene diol have been achieved.Copper coupling of straight-chain perfluoroalkyl iodides with the iodobenzene derivative in DMSO gave the desired compounds as DMSO complexes in 78-91 percent yield.