53179-09-2 Usage
Description
Sisomicin Sulfate is an aminoglycoside antibiotic derived from the microorganism Micromonospora inyoensis. It possesses potent antimicrobial properties and is effective against a wide range of gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, and Klebsiella species. Its mechanism of action involves binding to the bacterial 30S ribosomal subunit, which interferes with protein synthesis and ultimately leads to bacterial cell death.
Uses
Used in Pharmaceutical Industry:
Sisomicin Sulfate is used as an antibiotic for the treatment of various bacterial infections, particularly those caused by gram-negative bacteria. It is effective against a broad spectrum of bacteria, making it a valuable tool in the fight against antibiotic-resistant infections.
Used in Research and Development:
Sisomicin Sulfate is used as a reactant or reagent in the structural and kinetics study of self-assembling macrocyclic dimer natural product aminoglycoside 66-40C and its unnatural variants. This application aids in the development of new antibiotics and the understanding of their mechanisms of action, potentially leading to the creation of more effective treatments for bacterial infections.
Therapeutic Function
Antibiotic
Clinical Use
Although Sisomycin Sulfate has been approved for human use in theUnited States, it has not been marketed in this country. Itsantibacterial potency and effectiveness against aminoglycoside-inactivating enzymes resemble those of gentamicin.Sisomicin also exhibits pharmacokinetics and pharmacologicalproperties similar to those of gentamicin.
Safety Profile
Poison by intravenous,intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition itemits very toxic fumes of SOx and NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 53179-09-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,1,7 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 53179-09:
(7*5)+(6*3)+(5*1)+(4*7)+(3*9)+(2*0)+(1*9)=122
122 % 10 = 2
So 53179-09-2 is a valid CAS Registry Number.
InChI:InChI=1/2C19H37N5O7.5H2O4S/c2*1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;5*1-5(2,3)4/h2*3,9-18,24-27H,4-7,20-23H2,1-2H3;5*(H2,1,2,3,4)/t2*9?,10-,11+,12-,13+,14+,15-,16+,17?,18+,19-;;;;;/m00...../s1
