53189-89-2

Basic information

• Product Name: N-(benzylidene)morpholinium chloride
• Synonyms: N-(benzylidene)morpholinium chloride
• CAS NO: 53189-89-2
• Molecular Weight: 211.691
• Mol File: 53189-89-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-(benzylidene)morpholinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzylidene)morpholinium chloride(53189-89-2)
• EPA Substance Registry System: N-(benzylidene)morpholinium chloride(53189-89-2)

Safety Data

• Hazardous Substances Data: 53189-89-2(Hazardous Substances Data)

Upstream product

• 13368-42-8 4-(trimethylsilyl)morpholine 
• 100-52-7 benzaldehyde 

Downstream Products

• 148066-23-3 7,8,13,14-Tetrahydro-6-phenylquino<8,7-k><1,8>phenanthroline 
• 348136-83-4 1-methyl-3-(morpholin-4-yl-phenylmethyl)-1H-indole 
• 24685-08-3 1-(phenyl(morpholin-4-yl)methyl)naphthalen-2-ol 
• 52853-17-5 1-(morpholin-4-yl-phenyl-methyl)-isothiochroman-1-carbonitrile 
• 112881-42-2 5,6,8,9-Tetrahydro-7-phenylquino<8,7-b><1,10>phenanthroline 

Relevant articles and documents

Substituted 1 and 2 naphthol mannich bases

The invention relates to substituted 1 and 2 naphthol Mannich bases, a method for the production thereof, medicaments containing said compounds and the use of said compounds in the production of medicaments.

New Syntheses of Methyleniminium Salts from Carbonyl Compounds and from α-Chloro Ethers; an Access to Vinylogous Viehe Salts

Two methods for the synthesis of isolable methyleniminium salts and amidinium salts are presented.In the first case carbonyl compounds A are treated with a mixture of (dialkylamino)trimethylsilane (12) and chlorotrimethylsilane (13) or 12 and trimethylsilyl triflate (14) leading to the iminium chlorides F or iminium triflates G, respectively.With 12/13 the preparation of F is limited to non-enolizable aldehydes and dimethylformamide (10), while 12/14 enables the preparation of G, e.g. 23a-25a, 27a, also with ketones and with substituted amides.The second procedure is based on the treatment of α-chloro ethers L with 12.Both methods afford the Mannich reagent 16a in high yields.By reaction of the α-chloro ether 35 with 12 in diethyl ether the vinylogous Viehe salts 36a-c, e become available for the first time.The reaction pathways are discussed. - Key Words: Methyleniminium salts, preparation, mechanisms of formation / (Dialkylamino)trimethylsilanes / Ethers, α-chloro / Viehe salts, vinylogous