53213-82-4

Basic information

• Product Name: 3,3'-DIHEXYLOXACARBOCYANINE IODIDE
• Synonyms: BENZOXAZOLIUM, 3-HEXYL-2-[3-(3-HEXYL-2(3H)-BENZOXAZOLYLIDENE)-1-PROPENYL]-, IODIDE;DIOC6(3);3-HEXYL-2-[3-(3-HEXYL-2(3H)BENZOXAZOLYLIDENE)-1-PROPENYL]BENZOXAZOLIUM IODIDE;3-HEXYL-2-((E)-3-[3-HEXYL-1,3-BENZOXAZOL-2(3H)-YLIDENE]-1-PROPENYL)-1,3-BENZOXAZOL-3-IUM IODIDE;3,3'-DIHEXYLOXACARBOCYANINE IODIDE;NK 2280;3-hexyl-2-[3-(3-hexyl-2(3h)-benzoxazolylidene)-1-propenyl]-benzoxazoliuiod;3,3'-DIHEXYLOXACARBOCYANINE IODIDE, FOR FLUORESCENCE
• CAS NO: 53213-82-4
• Molecular Formula: C29H37IN2O2
• Molecular Weight: 572.52
• Product Categories: Cyanine
• Mol File: 53213-82-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 219-221 °C(lit.)
• Appearance: Red/Powder
• Density: 1.2837 (estimate)
• Solubility: Soluble in ethanol, methanol, dimethyl sulfoxide
• Sensitive: Light Sensitive
• BRN: 9312562
• CAS DataBase Reference: 3,3'-DIHEXYLOXACARBOCYANINE IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-DIHEXYLOXACARBOCYANINE IODIDE(53213-82-4)
• EPA Substance Registry System: 3,3'-DIHEXYLOXACARBOCYANINE IODIDE(53213-82-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: DM5285250
• F: 8
• TSCA: Yes
• Hazardous Substances Data: 53213-82-4(Hazardous Substances Data)

Usage

Description

3,3'-DIHEXYLOXACARBOCYANINE IODIDE is a red crystalline powder that is used as a cell-permeant, live-cell stain. It is highly selective for the endoplasmic reticulum (ER) and rarely stains mitochondria, unlike the conventional ER stain DiOC6(3). Staining at low concentrations does not appear to be toxic to cells.

Uses

Used in Cell Biology Research:
3,3'-DIHEXYLOXACARBOCYANINE IODIDE is used as an endoplasmic reticulum-tracker dye for visualizing and studying the structure and function of the ER in living cells. Its high selectivity for the ER and low toxicity at low concentrations make it a valuable tool for cell biology research.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,3'-DIHEXYLOXACARBOCYANINE IODIDE can be used as a fluorescent marker to track and analyze the distribution and dynamics of the endoplasmic reticulum in drug development and testing processes. This can help researchers understand the effects of drugs on cellular structures and functions, ultimately contributing to the development of more effective and safer medications.
Used in Biotechnology:
3,3'-DIHEXYLOXACARBOCYANINE IODIDE can also be employed in biotechnology applications, such as the development of biosensors or imaging techniques that rely on the detection and visualization of the endoplasmic reticulum. Its selective staining properties and low toxicity make it a suitable candidate for these applications.
Used in Diagnostics:
In the field of diagnostics, 3,3'-DIHEXYLOXACARBOCYANINE IODIDE can be utilized as a diagnostic tool for detecting and monitoring diseases or conditions that affect the endoplasmic reticulum, such as certain genetic disorders or metabolic diseases. Its ability to selectively stain the ER can aid in the early detection and diagnosis of these conditions, leading to more effective treatment and management strategies.

InChI:InChI=1/C29H37N2O2.HI/c1-3-5-7-13-22-30-24-16-9-11-18-26(24)32-28(30)20-15-21-29-31(23-14-8-6-4-2)25-17-10-12-19-27(25)33-29;/h9-12,15-21H,3-8,13-14,22-23H2,1-2H3;1H/q+1;/p-1