53224-97-8

Basic information

• Product Name: acetic acid-(5,6α-dibromo-5β-cholestan-3β-yl ester)
• CAS NO: 53224-97-8
• Molecular Weight: 588.507
• Mol File: 53224-97-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: acetic acid-(5,6α-dibromo-5β-cholestan-3β-yl ester)(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid-(5,6α-dibromo-5β-cholestan-3β-yl ester)(53224-97-8)
• EPA Substance Registry System: acetic acid-(5,6α-dibromo-5β-cholestan-3β-yl ester)(53224-97-8)

Safety Data

• Hazardous Substances Data: 53224-97-8(Hazardous Substances Data)

Upstream product

• 57-88-5 cholesterol 
• 604-35-3 Cholesteryl acetate 

Relevant articles and documents

Preparation of oxysterols by c–h oxidation of dibromocholestane with ru(Bpga) catalyst

Seven mono-and dihydroxycholesterols were prepared by direct C–H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh3 )] Cl; bpga = 2-(bis(pyridin-2-ylmethyl)amino)-N-(2,6-dimethylphenyl)acetamide)). Due to the high selectivity of the Ru(Bpga) complex for tertiary C–H, the reaction afforded a mixture of 25-, 20-, 17-, and 14-oxygenated cholesterols that could be easily separated by high-performance liquid chromatography. These results suggest that late-stage C–H oxidation could be a viable strategy for preparing candidate metabolites of biologically important molecules.