5323-75-1

Basic information

• Product Name: 2-benzoyl-2,3-dihydro-1H-inden-1-one
• Synonyms: 1H-inden-1-one, 2-benzoyl-2,3-dihydro-; 2-Benzoylindan-1-one
• CAS NO: 5323-75-1
• Molecular Formula: C₁₆H₁₂O₂
• Molecular Weight: 236.2653
• Mol File: 5323-75-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 402.6°C at 760 mmHg
• Flash Point: 150.8°C
• Density: 1.23g/cm³
• Vapor Pressure: 1.08E-06mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 2-benzoyl-2,3-dihydro-1H-inden-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzoyl-2,3-dihydro-1H-inden-1-one(5323-75-1)
• EPA Substance Registry System: 2-benzoyl-2,3-dihydro-1H-inden-1-one(5323-75-1)

Safety Data

• Hazardous Substances Data: 5323-75-1(Hazardous Substances Data)

Usage

General Description

2-benzoyl-2,3-dihydro-1H-inden-1-one, also known as α-tetralone, is a cyclic ketone compound with the molecular formula C15H12O. It is a pale yellow or colorless solid with a slightly floral odor and is commonly used as an intermediate in the synthesis of pharmaceuticals and fragrances. 2-benzoyl-2,3-dihydro-1H-inden-1-one is often used as a reactant in organic synthesis and can be found in a variety of industrial processes. α-tetralone is also used in the production of dyes, pigments, and polymers. It is important to handle this compound with care, as it may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation.

Upstream product

• 56409-75-7 ethyl 2-benzyl-3-oxo-3-phenylpropanoate 
• 201230-82-2 carbon monoxide 
• 153974-34-6 3-(2-iodophenyl)-1-phenylpropan-1-one 
• 98-88-4 benzoyl chloride 
• 577-16-2 2-Methylacetophenone 
• 61001-54-5 2-methyldibenzoylmethane 
• 50454-22-3 methyl (E)-2-(3-oxo-3-phenylprop-1-en-1-yl)benzoate 
• 62322-80-9 2-(2-Benzoylvinyl)benzoesaeure 
• 119-67-5 o-carboxybenzaldehyde 
• 40400-13-3 2-Iodobenzyl bromide 
• 98-86-2 acetophenone 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 83-33-0 inden-1-one 

Downstream Products

• 18398-39-5 Essigsaeure-(2-benzoyl-3-indenylester) 
• 83-33-0 inden-1-one 
• 65-85-0 benzoic acid 
• 1204747-37-4 C₂₀H₁₃N₃O₂S 
• 16003-58-0 3-Phenyl-2,4-dihydroindeno<1,2,c>pyrazol 
• 55849-38-2 (E)-2-(1-Acetoxybenzyliden)-1-indanon 
• 102012-62-4 4-[2-(3-oxo-3-phenyl-propyl)-benzoyl]-morpholine 
• 21012-53-3 1,3-diphenyl-4H-indeno[2,3-d]pyrazole 

Relevant articles and documents

Rhodium-Catalyzed Aerobic Decomposition of 1,3-Diaryl-2-diazo-1,3-diketones: Mechanistic Investigation and Application to the Synthesis of Benzils

The conversion of 1,3-diaryl-2-diazo-1,3-diketones to 1,2-daryl-1,2-diketones (benzils) is reported based on a rhodium(II)-catalyzed aerobic decomposition process. The reaction occurs at ambient temperatures and can be catalyzed by a few dirhodium carboxylates (5 mol %) under a balloon pressure of oxygen. Moreover, an oxygen atom from the O2 reagent is shown to be incorporated into the product, and this is accompanied by the extrusion of a carbonyl unit from the starting materials. Mechanistically, it is proposed that the decomposition may proceed via the interaction of a ketene intermediate resulting from a Wolff rearrangement of the carbenoid, with a rhodium peroxide or peroxy radical species generated upon the activation of molecular oxygen. The proposed mechanism has been supported by the results from a set of controlled experiments. By using this newly developed strategy, a large array of benzil derivatives as well as 9,10-phenanthrenequinone were synthesized from the corresponding diazo substrates in varying yields. On the other hand, the method did not allow the generation of benzocyclobutene-1,2-dione from 2-diazo-1,3-indandione because of the difficulty of inducing the initial rearrangement.

APPLICATION OF METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM IN PREPARATION OF 1,3-DICARBONYL COMPOUND IN CASCADE REACTION OF ELECTRON-DEFICIENT ALKENE COMPOUND

Provided is an application of a metal hydride/palladium compound system in the preparation of a 1,3-dicarbonyl compound in a cascade reaction of an electron-deficient alkene compound, said reaction comprising the following steps: under the protection of n

Method for preparing 1,3-dicarbonyl compound based on metal hydride/palladium compound system

The invention discloses a method for preparing a 1,3-dicarbonyl compound based on a metal hydride/palladium compound system. The method comprises the following steps: making a palladium compound and metal hydride suspend in a solvent under the protection