5324-84-5 Usage
Description
Sodium 1-octanesulfonate, also known as NaOS, is a white powder chemical compound with the formula C8H17NaO3S. It is an anionic detergent and a surface-active reagent, which can be used as an ion-pairing reagent in various analytical techniques. It is also known to interact with human serum albumin.
Uses
1. Used in Analytical Chemistry:
Sodium 1-octanesulfonate is used as an ion-pairing reagent for ultra-high performance liquid chromatography (UPLC) analysis with photodiode array detection. It is utilized to estimate paraquat (methyl viologen) in tissue homogenate and in the determination of dopamine and its metabolites in brain microdialysates using liquid chromatography combined with electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS).
2. Used in Suzuki Reaction:
Sodium 1-octanesulfonate serves as a reagent in the Suzuki reaction, a widely used method in organic chemistry for the formation of carbon-carbon bonds, particularly in the synthesis of biaryl compounds.
3. Used in Pharmaceutical Industry:
NaOS is used as a non-fluorinated surfactant with potential bactericidal efficacy against Escherichia coli, making it a valuable component in the development of new antimicrobial agents.
4. Used in Chromatography:
Sodium 1-octanesulfonate is employed as a reagent for high-performance liquid chromatography (HPLC) analysis of organic compounds, including peptides and proteins.
5. Used in Environmental Applications:
As an ion complexation agent for N-nitrosodiethanolamine, Sodium 1-octanesulfonate plays a role in environmental chemistry, particularly in the treatment and analysis of water and wastewater samples.
6. Used in Detergent Industry:
The monohydrate form of Sodium 1-octanesulfonate is used as an anionic detergent, contributing to its surface-active properties and making it a useful component in the formulation of various cleaning products.
Sources
https://www.sigmaaldrich.com/catalog/product/sial/74884?lang=en®ion=US
Orentien?, Asta, et al. "UPLC a Powerful Tool for the Separation of Imidazolium Ionic Liquid Cations." Chromatographia 73.1-2(2011): 17-24.
https://www.alfa.com/en/catalog/A14292/
https://www.alfa.com/en/catalog/015764/
Flammability and Explosibility
Notclassified
Purification Methods
Recrystallise it from absolute EtOH. [Beilstein 4 IV 58.]
Check Digit Verification of cas no
The CAS Registry Mumber 5324-84-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,2 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5324-84:
(6*5)+(5*3)+(4*2)+(3*4)+(2*8)+(1*4)=85
85 % 10 = 5
So 5324-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H18.Na.H2O3S/c1-3-5-7-8-6-4-2;;1-4(2)3/h3-8H2,1-2H3;;4H,(H,1,2,3)/q;+1;/p-1
5324-84-5Relevant articles and documents
Jensen,Lingafelter
, p. 1946 (1944)
One-Step Synthesis of Esters of Aliphatic β-Chloro Sulfonic Acids. Their Sequential Conversion to Other Sulfonic Acid Derivatives
Heller, Morgan S.,Lorah, Dennis P.,Cox, Charles G.
, p. 134 - 137 (2007/10/02)
A one-step synthesis of methyl 2-chlorohexane-1- and 2-chlorooctane-1-sulfonate by the novel free-radical addition of methyl chlorosulfonate to 1-hexene and 1-octene, respectively, is reported.These products were converted by standard techniques into the corresponding sodium and benzylthiuronium β-chlorosulfonic acid salts and sulfonyl chlorides.Dehydrochlorination of these latter products with triethylamine affored regiospecific formation of trans-α,β-unsaturated sulfonyl chlorides, which were transformed by conventional methods into sodium and benzylthiuroniumunsaturated and saturated sulfonic acid salts.Eleven new compositions of matter are reported.