53256-19-2

Basic information

• Product Name: (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester
• Synonyms: (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester;(Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester;(Z)-3-Amino-3-phenyl-acrylic acid ethyl ester
• CAS NO: 53256-19-2
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.22642
• Mol File: 53256-19-2.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 164-165 °C(Press: 10 Torr)
• Appearance: /
• Density: 1.099
• PKA: 3.93±0.70(Predicted)
• CAS DataBase Reference: (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester(53256-19-2)
• EPA Substance Registry System: (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester(53256-19-2)

Safety Data

• Hazardous Substances Data: 53256-19-2(Hazardous Substances Data)

Usage

General Description

(2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester is a chemical compound that belongs to the class of amino acids. It is an ethyl ester derivative of the amino acid phenylalanine and is commonly used in the field of organic chemistry and biochemistry. (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester is primarily used in the synthesis of various pharmaceuticals and as a building block for the production of peptide-based drugs. It is also a crucial component in the development of new drug candidates and protein-based therapeutics. In addition, (2Z)-3-Amino-3-phenyl-2-propenoic acid ethyl ester is utilized in the research and development of new materials and compounds with potential biological and therapeutic applications. Overall, this chemical compound plays a significant role in the advancement of pharmaceutical and medical research.

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 100-47-0 benzonitrile 
• 98-86-2 acetophenone 
• 625-28-5 Isovaleronitrile 
• 105-36-2 ethyl bromoacetate 
• 98-88-4 benzoyl chloride 
• 141-97-9 ethyl acetoacetate 
• 108-86-1 bromobenzene 
• 105-56-6 ethyl 2-cyanoacetate 
• 698-16-8 benzohydroximoyl chloride 
• 6148-64-7 ethyl potassium malonate 
• 141-78-6 ethyl acetate 
• 129207-82-5 ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate 

Downstream Products

• 53256-29-4 (E)-4-[1-Amino-1-phenyl-meth-(Z)-ylidene]-pent-2-enedioic acid 5-ethyl ester 1-methyl ester 
• 53256-35-2 (2Z,4Z)-5-Amino-4-ethoxycarbonyl-3-methoxycarbonyl-5-phenyl-penta-2,4-dienoic acid methyl ester 
• 53256-30-7 (E)-4-[1-Amino-1-phenyl-meth-(Z)-ylidene]-pent-2-enedioic acid diethyl ester 
• 60-80-0 antipyrine 
• 58787-21-6 ethyl 2-phenyl-4-methyl-3-pyridinecarboxylate 
• 6335-76-8 3-amino-3-phenylpropionic acid ethyl ester 
• 33912-78-6 ethyl (Z)-β-phenyl-β-(acetylamino)acrylate 
• 25095-49-2 2,4-diphenylpyrimidine-5-carboxylic acid 
• 3189-40-0 N-ethyl‐5‐hydroxyl‐2‐phenyl-1H-indole‐3‐ylcarboxylic acid 

Relevant articles and documents

Trifluoroethanol as a Unique Additive for the Chemoselective Electrooxidation of Enamines to Access Unsymmetrically Substituted NH-Pyrroles

An electrochemical method for the synthesis of unsymmetrically substituted NH-pyrroles is described. The synthetic strategy comprises a challenging heterocoupling between two structurally diverse enamines via sequential chemoselective oxidation, addition,

Cu-Catalyzed Denitrogenative Transannulation of 3-Aminoindazoles to Assemble 1-Aminoisoquinolines and 3-Aminobenzothiophenes

We disclose a novel Cu-catalyzed denitrogenative transannulation of 3-aminoindazoles to afford diverse functionalized 3-aminobenzothiophenes and 1-aminoisoquinolines, in which denitrogenative transannulation of 3-aminoindazoles is reported for the first t

Copper-Catalyzed One-pot Synthesis of Pyrimidines from Amides, N,N′-dimethylformamide dimethylacetal, and Enamines

A versatile copper catalyzed one-pot synthesis of diversely substituted pyrimidines directly from amides, N,N′-dimethylformamide dimethylacetal (DMF?DMA) and enamines has been established. The reaction involved the two C?N bonds and one C?C bond formation by formal [2+1+3] annulation approach to pyrimidines. This protocol is based on the use of readily available primary amides, DMF?DMA and enamines to install di- and tri-substituted pyrimidine structure with diverse functionality in one-pot manner, which makes this strategy to be appealing for the medicinal chemistry. (Figure presented.).