53312-77-9

Basic information

• Product Name: 2-AMINO-3-CHLOROBENZONITRILE
• Synonyms: 2-AMINO-3-CHLOROBENZONITRILE;3-CHLOROANTHRANILONITRILE;Benzonitrile, 2-amino-3-chloro-;2- aMino-3-chloro benzoylnitrile
• CAS NO: 53312-77-9
• Molecular Formula: C₇H₅ClN₂
• Molecular Weight: 152.58
• Product Categories: Aromatic Nitriles;Nitrile
• Mol File: 53312-77-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 94-96℃
• Boiling Point: 266.935 °C at 760 mmHg
• Flash Point: 115.239 °C
• Appearance: /
• Density: 1.33 g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.61
• Storage Temp.: 2-8°C(protect from light)
• PKA: -0.13±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-3-CHLOROBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-CHLOROBENZONITRILE(53312-77-9)
• EPA Substance Registry System: 2-AMINO-3-CHLOROBENZONITRILE(53312-77-9)

Safety Data

• RIDADR: 3439
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 53312-77-9(Hazardous Substances Data)

Usage

General Description

2-Amino-3-chlorobenzonitrile is a chemical compound with the molecular formula C7H5ClN2. It is a pale yellow to light brown powder that is insoluble in water. 2-AMINO-3-CHLOROBENZONITRILE is commonly used as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. It is also employed in the synthesis of various other organic compounds. 2-Amino-3-chlorobenzonitrile is known to be a potential irritant to the skin, eyes, and respiratory system, and may be harmful if ingested. It is important to handle this chemical with care and follow proper safety precautions when working with it.

InChI:InChI=1/C7H5ClN2/c8-6-3-1-2-5(4-9)7(6)10/h1-3H,10H2

Upstream product

• 608-31-1 2,6-Dichloroaniline 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 397322-82-6 2-amino-3-chlorophenylformaldehyde 
• 913731-14-3 6-(4,4-dimethyl-1,3-oxazolin-2-yl)-2-chlorophenylamine 
• 402842-43-7 3-chloro-2-(5-oxo-5,6-dihydro-2H-thiopyran-3-ylamino)-benzonitrile 
• 875629-19-9 3-chloro-2-pyrrol-1-yl-benzylamine 
• 56762-32-4 1-(2-amino-3-chlorophenyl)ethan-1-one 
• 857594-97-9 2-chloro-6-(prop-1-en-2-yl)aniline 
• 5621-66-9 [2-amino-3-chlorophenyl]phenylmethanone 

Relevant articles and documents

A kind of 3,4-dichloro-thiazole derivatives and process for their preparation and use

The invention provides 3,4-dichloro isothiazole derivatives, their preparation method and application. The invention relates to a heterocyclic compound containing 3,4-dichloro isothiazol, and the compound is represented by the following chemical structural general formula. The invention discloses the structural general formula of the compound, a synthetic method of the compound and applications of the compound as pesticide, bactericide, anti-plant virus agent, and plant activator, and a technology of mixing the compound with agriculturally acceptable auxiliary agents or synergists for preparing pesticide, bactericide, anti-plant virus agent, and plant activator. The invention further discloses the combined application of the compound and the commercial pesticide, bactericide, anti-plant virus agent, and plant activator in controlling diseases, insect pests, and virus diseases in agriculture, forestry and gardening, and a preparation method of the compound and the commercial pesticide, bactericide, anti-plant virus agent, and plant activator.

Evidence for Homo-Conjugation between Two Revolving 14π-Electron Systems in 10b-Methyl-10c-[2-(10b,10c-dimethyl-10b,10c-dihydropyrenyl)]-10b, 10c-dihydropyrene

Ring contraction followed by an elimination reaction on anti-9-methyl-18-trans-2-(10b,10c-dimethyl-10b,10c-dihydropyrenyl)-2,11-dithia[3,3]metacyclophane gave the desired compound 10b-methyl-10c-[2-(10b,10c-dimethyl-10b,10c-dihydropyrenyl)]-10b,10c-dihydropyrene. 1H NMR spectroscopic analysis indicated a ring current effect over a considerable distance from the macro-molecular plane of each of the aromatic rings with the two π systems freely rotating. Bathochromic shifts and peak broadening in its electronic spectrum clearly supports the presence of through-space π?π interactions between the two aromatic rings. This should serve as a good model to verify homo-conjugation effect in such a novel system where the two π systems are freely revolving. Copyright