5333-29-9

Basic information

• Product Name: 1-(3,5-dimethoxyphenyl)pentan-1-one
• CAS NO: 5333-29-9
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.2802
• Mol File: 5333-29-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 320.6°C at 760 mmHg
• Flash Point: 138.7°C
• Density: 1.017g/cm³
• Vapor Pressure: 0.000315mmHg at 25°C
• Refractive Index: 1.493
• CAS DataBase Reference: 1-(3,5-dimethoxyphenyl)pentan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-dimethoxyphenyl)pentan-1-one(5333-29-9)
• EPA Substance Registry System: 1-(3,5-dimethoxyphenyl)pentan-1-one(5333-29-9)

Safety Data

• Hazardous Substances Data: 5333-29-9(Hazardous Substances Data)

Usage

Class of chemicals

Phenethylamines

Structural relation

Amphetamines

Physical state

White crystalline solid

Molecular weight

222.28 g/mol

Availability

Powder or tablet form

Properties

Stimulant and hallucinogenic

Effects

Euphoria, increased energy, altered perceptions

Medical use

Not approved

Legal status

Controlled substance in many countries

Potential issues

Abuse and dependence

Upstream product

• 2150-37-0 methyl 3,5-dimethoxybenzoate 
• 109-72-8 n-butyllithium 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 538-75-0 dicyclohexyl-carbodiimide 
• 17213-57-9 3,5-dimethoxybenzoyl chloride 
• 97025-16-6 3-(3,5-dimethoxyphenyl)-3-oxopropionic acid ethyl ester 
• 873967-69-2 3-((Ξ)-butylidene)-5,7-dimethoxy-phthalide 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 109-65-9 1-bromo-butane 
• 19179-31-8 3,5-dimethoxy-benzonitrile 
• 140464-67-1 3,4,5-Trimethoxybenzaldehyde dibutyl acetal 
• 38228-28-3 1-(1-hydroxypentyl)-3,5-dimethoxybenzene 
• 3431-67-2 di-n-butylcadmium 
• 855469-97-5 2,4-dimethoxy-6-valeryl-benzoic acid 

Downstream Products

• 500885-51-8 2-butyl-2-(3,5-dimethoxy-phenyl)-[1,3]dithiolane 
• 22976-40-5 1,3-dimethoxy-5-pentylbenzene 
• 500-66-3 Olivetol 
• 58545-48-5 (E)-1,3-dimethoxy-5-(pent-1-en-1-yl)benzene 
• 83816-36-8 5-(5-Methylnon-5-yl)resorcinol Dimethyl Ether 
• 104388-21-8 1-(1,1-Dibutyl-pentyl)-3,5-dimethoxy-benzene 
• 104388-14-9 1-(1-Butyl-1-methylselanyl-pentyl)-3,5-dimethoxy-benzene 
• 330855-39-5 5-(2-butyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol 
• 22930-08-1 1,3-dimethoxy-5-(2-methylhexan-2-yl)benzene 
• 83816-40-4 Lithium; 5-(3,5-dimethoxy-phenyl)-nonan-5-olate 
• 50833-08-4 3,5-Dimethoxyphenyl-di-n-butylkarbinol 

Relevant articles and documents

Preparation method of 3,5-dihydroxyamylbenzene

The invention provides a preparation method of 3,5-dihydroxyamylbenzene. The preparation method comprises the following steps: with a 3,5-dialkoxy benzoate compound as a raw material, subjecting the 3,5-dialkoxy benzoate compound to reacting with valeronitrile to generate a beta-ketone nitrile compound, hydrolyzing a cyano group to generate a carboxylic acid compound, performing a decarboxylation reaction to obtain 3,5-dialkoxyphenylpentanone, performing Huang Ming-long reaction or catalytic hydrogenation to convert 3,5-dialkoxyphenylpentanone into 3,5-dialkoxyamylbenzene, and finally, reducing an alkoxy group into a phenolic hydroxyl group so as to obtain 3,5-dihydroxyamylbenzene. The preparation method provided by the invention overcomes the defects of high cost, complex route, low yield, poor purity and the like of traditional processes.

A simple synthesis of ketone from carboxylic acid using tosyl chloride as an activator

An effective process for the conversion of carboxylic acid to ketone has been discovered. In this process, carboxylic acid has been activated using p-toluene sulphonyl group. Under the optimized condition, aromatic, aliphatic heteroaromatic carboxylic acids have been proved to be good substrates for this methodology. The byproduct of this reaction can be removed very easily during work up process. Also, one equivalent of organometallic reagent is sufficient to complete this transformation.

Cannabinoid derivatives, methods of making, and use thereof

1′-substituted cannabinoid derivatives of delta-8-tetrahydrocannabinol, delta-9-tetrahydrocannabinol, and delta-6a-10a-tetrahydrocannabinol that have affinity for the cannabinoid receptor type-1 (CB-1) and/or cannabinoid receptor type-2 (CB-2). Compounds