53338-20-8

Basic information

• Product Name: 2-Amino-1-naphthalenethiol
• Synonyms: 2-Amino-1-naphthalenethiol
• CAS NO: 53338-20-8
• Molecular Formula: C₁₀H₉NS
• Molecular Weight: 175.25
• Mol File: 53338-20-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 110 °C(Solv: ethanol (64-17-5))
• Boiling Point: 353.0±15.0 °C(Predicted)
• Appearance: /
• Density: 1.265±0.06 g/cm3(Predicted)
• PKA: 7.66±0.30(Predicted)
• CAS DataBase Reference: 2-Amino-1-naphthalenethiol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-1-naphthalenethiol(53338-20-8)
• EPA Substance Registry System: 2-Amino-1-naphthalenethiol(53338-20-8)

Safety Data

• Hazardous Substances Data: 53338-20-8(Hazardous Substances Data)

Upstream product

• 1203-55-0 naphtho[2,1-d]thiazol-2-amine 
• 135-19-3 β-naphthol 
• 581-97-5 2-acetylaminonaphthalene 
• 7664-93-9 sulfuric acid 
• 234-50-4 naphtho[2,1-d][1,2,3]thiadiazole 
• 3292-52-2 naphth<2,1-d>-1,2,3-dithiazol-2-oxide 
• 91-59-8 naphthalen-2-ylamine 
• 2476-69-9 2-Amino-1-thiocyanatonaphthalene 

Downstream Products

• 143667-63-4 2H-2-Phenylnaphtho<1,2-b><1,4>thiazin-3(4H)-one 
• 17931-26-9 2-mercaptonaphtho<2,1-d>thiazole 
• 17931-24-7 naphtho[2,1-d]thiazol-2(3H)-one 
• 128232-04-2 (2R,3S)-3-<(2-amino-1-naphthalenyl)thio>-2-hydroxy-3-(4-methoxyphenyl)propanoic acid (1R,2S)-2-phenylcyclohexyl ester hydrochloride 
• 108383-87-5 (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-5-[2-(dimethylamino)ethyl]naphtho[1,2-b][1,4]thiazepin-4(5H)-one 
• 108383-96-6 (+)-cis-3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-<2-(dimethylamino)ethyl>naphtho<1,2-b><1,4>thiazepin-4(5H)-one hydrochloride 
• 125226-69-9 (+)-3-<(2-amino-1-naphthalenyl)thio>-2-hydroxy-3-(4-methoxyphenyl)propanoic acid 
• 125276-26-8 (2S,3S)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)naphtho[1,2-b][1,4]thiazepin-4(5H)-one 
• 14889-08-8 2-hydrazinonaphtho<2,1-d>thiazole 
• 17931-25-8 2-chloronaphtho<2,1-d>thiazole 
• 234-47-9 naphtho[2,1-d][1,3]thiazole 

Relevant articles and documents

A Convenient Synthesis of 2-Aminonaphthalene-1-thiol

Reaction of 2-acetamidonaphthalene with sulfur monochloride gives the corresponding naphthothiazathiolium chloride, which on sequential hydrolyses with sodium bicarbonate and sodium hydroxide affords 2-aminonaphthalene-1-thiol.

Convenient synthesis of 2-aminonaphthalene-1-thiol and 3-aminoquinoline-4-thiol and cyclocondensations to 1,4-thiazino and 1,4-thiazepino derivatives

An improved method for the synthesis of 2-aminonaphthalene-1-thiol and an alternative procedure for the preparation of 3-aminoquinoline-4-thiol are described. From these intermediates some 1,4-thiazino and 1,4-thiazepino tricyclic derivatives have been prepared.

SYNTHESIS OF HETEROCYCLES : SYNTHESIS OF NAPHTHO-TRIAZOLOTRIAZEPINES

Some new fluorinated naphthothiazolotriazepines have been synthesized by condensation of 2-hydrazinonaphthothiazoles with 1,3-diketones.