5335-82-0

Basic information

• Product Name: Ethanone, 1,1'-(dithiodi-4,1-phenylene)bis-
• Synonyms: Acetophenone, 4,4''-dithiodi- (6CI);Acetophenone,4',4'''-dithiodi- (7CI,8CI);NSC 986
• CAS NO: 5335-82-0
• Molecular Formula: C₁₆H₁₄O₂S₂
• Molecular Weight: 302.418
• Mol File: 5335-82-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 461.1 °C at 760 mmHg
• Flash Point: 199.3 °C
• Density: 1.27 g/cm³
• CAS DataBase Reference: Ethanone, 1,1'-(dithiodi-4,1-phenylene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1,1'-(dithiodi-4,1-phenylene)bis-(5335-82-0)
• EPA Substance Registry System: Ethanone, 1,1'-(dithiodi-4,1-phenylene)bis-(5335-82-0)

Safety Data

• Hazardous Substances Data: 5335-82-0(Hazardous Substances Data)

Usage

General Description

Ethanone, 1,1'-(dithiodi-4,1-phenylene)bis- is a chemical compound with the molecular formula C14H12S2O2. It is a dithiobisaryl ketone, which means it contains two sulfur atoms and two aromatic rings. Ethanone, 1,1'-(dithiodi-4,1-phenylene)bis- is used in various industrial applications, including as a crosslinking agent in polymer chemistry and as a building block for the synthesis of other organic compounds. It is important to handle this substance with care, as it can be hazardous if not used properly.

Upstream product

• 26824-04-4 1-(4-(phenyldisulfanyl)phenyl)ethan-1-one 
• 1778-09-2 4-(Methylthio)acetophenone 
• 3814-20-8 4-mercaptoacetophenone 
• 350-47-0 1-(4-acetylphenyl)diazonium tetrafluoroborate 
• 1788-10-9 4-Acetylbenzenesulfonyl chloride 
• 98-09-9 benzenesulfonyl chloride 
• 99-90-1 para-bromoacetophenone 
• 13329-40-3 4-Iodoacetophenone 
• 103-04-8 (phenylthio)acetic acid 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 931-59-9 benzenesulfenyl chloride 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 99-93-4 4-Hydroxyacetophenone 
• 109613-00-5 4-acetophenyl triflate 

Downstream Products

• 1565-17-9 4-acetylbenzenesulfonamide 
• 3814-20-8 4-mercaptoacetophenone 
• 161386-58-9 4'-[4-(1,2-dihydroxyprop-2-yl)thien-2-ylthio]acetophenone 
• 156538-37-3 4'-(4-bromothien-2-ylthio)acetophenone ethylene acetal 
• 161386-57-8 4'-[4-(2-hydroxy-1-tetrahydropyran-2-yloxyprop-2-yl)thien-2-ylthio]acetophenone ethylene acetal 
• 161386-60-3 4'-<<4-(2,2,4-trimethyl-1,3-dioxolan-4-yl)thien-2-yl>thio>acetophenone 
• 156538-36-2 bis<4-(2-methyl-1,3-dioxolan-2-yl)phenyl> disulfide 
• 14428-56-9 1-(4-thiocyanatophenyl)ethan-1-one 
• 40973-70-4 1-(4-mercapto-phenyl)-ethanone; potassium salt 

Relevant articles and documents

A novel dual-nano assisted synthesis of symmetrical disulfides from aryl/alkyl halides

Here, we have reported a novel approach towards dual-nano assisted synthesis of disulfides from coupling of alkyl/aryl halides and sulfur nanoparticles. The indium oxide nanoparticles as catalyst expedite the conversion and sulfur nanoparticle notably enhances the miscibility, providing a faster, high yielding and cost-effective process in ethanol-water system. The method has synthetic advantages in terms of mild reaction framework, catalyst regeneration, and absence of any sulfide or polysulfide linkage as by-product leading to a column free synthesis. A variety of alkyl, aryl and heteroaryl symmetrical disulfides are obtained in good to excellent yields up to exceeding 98%.

3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) mediated metal-free mild oxidation of thiols to disulfides in aqueous medium

Thiols are efficiently oxidized to disulfides (RSSR) in the presence of 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) in aqueous medium, as well as in the absence of a solvent under mild and metal-free conditions. A broad range of alkyl, aryl and heterocyclic symmetrical disulfides can be easily obtained in almost quantitative yields. The X-ray single crystal structure of 2-aminocyclopent-1-ene-1-carbothioic dithioperoxyanhydride (disulfide obtained from 2-aminocyclopentene-1-dithiocarboxylic acid, ACDA) is reported. The reaction mechanism has been studied thoroughly. It is shown that the reaction proceeds through the formation of an organosulphur radical. Pytz interacts with thiol to accept one electron and produces an organosulphur radical. Pytz ultimately accepts two electrons to form H2pytz and is capable of oxidizing 2 equivalents of thiols.

Electrochemical transformation of diazonium salts into diaryl disulfides

Electrolyses of aryldiazonium tetrafluoroborates in CS2/EtOH and Bu4NClO4, as the solvent-supporting electrolyte system, led to the corresponding diaryl disulfides in good yields.