5336-56-1

Basic information

• Product Name: (4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone
• CAS NO: 5336-56-1
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.2705
• Mol File: 5336-56-1.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 407.5°C at 760 mmHg
• Flash Point: 174°C
• Density: 1.139g/cm³
• Vapor Pressure: 3.18E-07mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: (4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone(5336-56-1)
• EPA Substance Registry System: (4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone(5336-56-1)

Safety Data

• Hazardous Substances Data: 5336-56-1(Hazardous Substances Data)

Usage

Description

(4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone, also known as a benzophenone derivative, is a chemical compound with the molecular formula C15H14O2. It is a ketone derivative of phenyl and is characterized by its white to off-white powder appearance. (4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone has a molecular weight of 226.27 g/mol and features a hydroxy group and two methyl groups attached to a central phenyl ring, with a carbonyl group connected to the adjacent phenyl ring. Its versatile reactivity and functional group compatibility make it a valuable intermediate in the synthesis of various organic compounds.

Uses

Used in Organic Synthesis:
(4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone is used as an intermediate in organic synthesis for the production of a wide range of compounds. Its unique structure and functional groups allow for further chemical reactions, making it a valuable building block in the creation of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone is used as a key component in the synthesis of various drugs. Its versatile chemical properties enable the development of new medications with specific therapeutic effects.
Used in Agrochemicals:
(4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone also finds application in the agrochemical sector, where it is utilized in the development of chemicals for agricultural purposes, such as pesticides and herbicides. Its reactivity and structural features contribute to the creation of effective and targeted agrochemical products.
Used in Specialty Chemicals:
(4-hydroxy-3,5-dimethylphenyl)(phenyl)methanone is employed in the production of specialty chemicals, which are tailored for specific industries and applications. Its unique properties and reactivity make it a valuable component in the development of these specialized products.

Upstream product

• 1871-36-9 2,6-dimethylphenyl benzoate 
• 1004-66-6 2-methoxy-1,3-dimethylbenzene 
• 98-88-4 benzoyl chloride 
• 576-26-1 2.6-dimethylphenol 
• 3393-96-2 p-nitrobenzanilide 
• 3689-45-0 3,3-bis(4-hydroxy-3,5-dimethylphenyl)isobenzofuran-1(3H)-one 
• 85-44-9 phthalic anhydride 
• 65-85-0 benzoic acid 
• 85604-74-6 2-(4-hydroxy-3,5-dimethylbenzoyl)benzoic acid 
• 14753-87-8 (4-methoxy-3,5-dimethylphenyl)(phenyl)methanone 

Downstream Products

• 93950-00-6 [3,5-Dimethyl-4-(2-methylamino-ethoxy)-phenyl]-phenyl-methanone 
• 94914-27-9 [4-(2-Dimethylamino-ethoxy)-3,5-dimethyl-phenyl]-phenyl-methanone 
• 95289-44-4 [4-(2-Diethylamino-ethoxy)-3,5-dimethyl-phenyl]-phenyl-methanone 
• 3734-35-8 4-benzoylxylocholine methylsulphate 
• 61400-67-7 4-phenylmethylene-2,6-dimethyl-2,5-cyclohexadien-1-one 

Relevant articles and documents

Synthesis, characterization, docking study and antimicrobial activity of 2-(4-benzoylphenoxy)-1-[2-(1-methyl-1H-indol-3-yl)methyl)-1H-benzo[d]imidazol-1-yl] ethanone derivatives

The occurrence of drug-resistant bacterial infections impulses the development of new antibacterial agents that own a mechanism of action different from traditional antibiotics. From the earlier days, benzophenone, indole and benzimidazole moieties alone

TBAB-catalyzed 1,6-conjugate sulfonylation of paraquinone methides: A highly efficient approach to unsymmetrical gem-diarylmethyl sulfones in water ?

A highly efficient sulfonylation of para-quinone methides with sulfonyl hydrazines in water has been developed on the basis of the mode involving a tetrabutyl ammonium bromide (TBAB)-promoted sulfa-1,6-conjugated addition pathway. This reaction provides a green and sustainable method to synthesize various unsymmetrical diarylmethyl sulfones, showing good functional group tolerance, scalability, and regioselectivity. Further transformation of the resulting diarylmethyl sulfones provides an efficient route to some functionalized molecules.

Enantioselective Spirocyclopropanation of para-Quinone Methides Using Ammonium Ylides

The use of Cinchona alkaloid-based chiral ammonium ylides allows for the first highly enantioselective and broadly applicable spirocyclopropanation reactions of para-quinone methides. This strategy provides a straightforward protocol toward the chiral spiro[2.5]octa-4,7-dien-6-one skeleton, which is a frequently found structural motif in important biologically active molecules.