53363-87-4

Basic information

• Product Name: Z-LEU-OH DCHA
• Synonyms: N-CARBOBENZOXY-L-LEUCINE DICYCLOHEXYLAMINE SALT;N-ALPHA-CARBOBENZOXY-L-LEUCINE-DICYCLOHEXYLAMMONIUM SALT;N-ALPHA-CBZ-L-LEUCINE DICYCLOHEXYLAMMONIUM SALT;Z-L-LEUCINE DCHA;Z-L-LEUCINE DICYCLOHEXYLAMMONIUM SALT;Z-L-LEU-OH DCHA;Z-LEU-OH DCHA;CBZ-L-LEUCINE DCHA
• CAS NO: 53363-87-4
• Molecular Formula: C₁₂H₂₃N*C₁₄H₁₉NO₄
• Molecular Weight: 446.62
• EINECS: 258-497-7
• Product Categories: Z-Amino Acids and Derivatives;Z-Amino acid series
• Mol File: 53363-87-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 612.2 °C at 760 mmHg
• Flash Point: 324 °C
• Appearance: /
• Vapor Pressure: 1.28E-08mmHg at 25°C
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: Z-LEU-OH DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: Z-LEU-OH DCHA(53363-87-4)
• EPA Substance Registry System: Z-LEU-OH DCHA(53363-87-4)

Safety Data

• Hazardous Substances Data: 53363-87-4(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C14H19NO4.C12H23N/c1-10(2)8-12(13(16)17)15-14(18)19-9-11-6-4-3-5-7-11;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h3-7,10,12H,8-9H2,1-2H3,(H,15,18)(H,16,17);11-13H,1-10H2

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Relevant articles and documents

KINETICS OF THE ALKALINE HYDROLYSIS OF SEVERAL N-BENZYLOXYCARBONYLDIPEPTIDE METHYL AND ETHYL ESTERS

The reaction rates of the alkaline hydrolysis of synthesized N-protected dipeptide methyl and ethyl esters were studied systematically.From the kinetic data the energies of activation, the pre-exponential factors and the reference values at 40 deg C were calculated.The rate of hydrolysis shows to be strongly dependent on the C-terminal amino acid in the sequence Gly >> Ala/Met/Phe > Leu >> Val/Pro.Surprisingly the N-terminal amino acid also exerts an effect, but in a different sequence.N-Terminal Phe in particular shows a relative accelerating effect.Remarkable is the significantly faster ester hydrolysis of glycine containing dipeptide ethyl esters in ethanol/water compared to the corresponding methyl esters in methanol/water.