5343-35-1

Basic information

• Product Name: 1-Amino-pentan-2-ol
• Synonyms: 1-Amino-pentan-2-ol
• CAS NO: 5343-35-1
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.17
• Product Categories: pharmacetical
• Mol File: 5343-35-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 195.6°C at 760 mmHg
• Flash Point: 72.1°C
• Appearance: /
• Density: 0.915g/cm³
• Vapor Pressure: 0.108mmHg at 25°C
• Refractive Index: 1.449
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 12.92±0.35(Predicted)
• CAS DataBase Reference: 1-Amino-pentan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Amino-pentan-2-ol(5343-35-1)
• EPA Substance Registry System: 1-Amino-pentan-2-ol(5343-35-1)

Safety Data

• Hazardous Substances Data: 5343-35-1(Hazardous Substances Data)

Usage

Description

1-Amino-pentan-2-ol, with the CAS number 5343-35-1, is an organic compound that serves as a crucial building block in the development of various pharmaceuticals and chemical products. It is characterized by its unique molecular structure, which features an amino group and a hydroxyl group attached to a pentane chain. This structure endows 1-Amino-pentan-2-ol with versatile properties and potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
1-Amino-pentan-2-ol is used as a phenylethanolamine methyltransferase (PEMT) substrate for the synthesis of various pharmaceutical compounds. PEMT is an enzyme that plays a vital role in the biosynthesis of neurotransmitters and hormones, such as dopamine, norepinephrine, and epinephrine. By acting as a substrate for this enzyme, 1-Amino-pentan-2-ol contributes to the production of these essential molecules, which are crucial for maintaining proper brain function and regulating various physiological processes.
Used in Drug Design and Development:
1-Amino-pentan-2-ol is also utilized in the field of drug design and development, particularly for creating computer-aided ligandand receptor-based drugs. Its unique molecular structure allows it to be used as a starting point or a key intermediate in the synthesis of novel drug candidates. By employing computer-aided drug design techniques, researchers can identify and optimize the interactions between 1-Amino-pentan-2-ol and its target receptors, leading to the development of more effective and selective therapeutic agents.

InChI:InChI=1/C5H13NO/c1-2-3-5(7)4-6/h5,7H,2-4,6H2,1H3

Upstream product

• 74-90-8 hydrogen cyanide 
• 123-72-8 butyraldehyde 
• 64-17-5 ethanol 
• 85149-05-9 1-nitro-pent-3-en-2-ol 
• 2224-37-5 1-nitropentan-2-ol 
• 1436-34-6 1,2-Epoxyhexane 

Relevant articles and documents

2-OXO-1,3-OXAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES

The present invention relates to 2-oxo-1,3-oxazolidinyl imidazothiadiazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.

JNK INHIBITOR

A JNK inhibitor containing a compound having an isoquinolinone skeleton or a salt thereof, such as a compound represented by the formula wherein ring A and ring B are each an optionally substituted benzene ring, X is -O-, -N=, -NR3- or -CHR3-, R2 is an acyl group, an optionally esterified or thioesterified carboxyl group, an optionally substituted carbamoyl group or an optionally substituted amino group and the like, a broken line shows a single bond or a double bond, and R1 is a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like, and the like.