53458-14-3

Basic information

• Product Name: Ethanone, 2-(4-bromophenyl)-2-hydroxy-1-phenyl-
• CAS NO: 53458-14-3
• Molecular Formula: C14H11BrO2
• Molecular Weight: 291.144
• Mol File: 53458-14-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-(4-bromophenyl)-2-hydroxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-(4-bromophenyl)-2-hydroxy-1-phenyl-(53458-14-3)
• EPA Substance Registry System: Ethanone, 2-(4-bromophenyl)-2-hydroxy-1-phenyl-(53458-14-3)

Safety Data

• Hazardous Substances Data: 53458-14-3(Hazardous Substances Data)

Upstream product

• 5908-41-8 benzoyltrimethylsilane 
• 1122-91-4 4-bromo-benzaldehyde 
• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 536-74-3 phenylacetylene 
• 17452-05-0 (1-methyl-1H-benzo[d]imidazol-2-yl)(phenyl)methanol 
• 1681-56-7 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide 
• 102034-67-3 2-benzoyloxy-2(4-bromophenyl)-1-phenylethanone 
• 613-90-1 benzoyl cyanide 
• 108-86-1 bromobenzene 
• 1074-12-0 phenylglyoxal hydrate 

Downstream Products

• 39229-12-4 4-bromobenzil 

Relevant articles and documents

Visible Light Enabled Formal Cross Silyl Benzoin Reaction as an Access to α-Hydroxyketones

In this work, a visible-light enabled coupling of acylsilanes with aldehydes to give a range of cross-benzoin type products α-hydroxyketones is described. The reaction could proceed at ambient temperature, with the irradiation of low energy visible light, and without addition of photosensitizer or any other additives. (Figure presented.).

Synthesis and reactivities of 1,3-dimethyl-2-(α-hydroxy-benzyl)imidazolium and 1,3-dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodides

1,3-Dimethyl-2-(α-hydroxybenzyl)benzimidazolium iodide (3a) was synthesized from 1-methylbenzimidazole (10) through two steps involving lithiation and quaternization. Treatment of 3a with 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (6) afforded 4-benzoyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine (15a). 4-Benzoylquinazoline (14a) and 7-benzoyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (16a) were given by reaction of 3a with 4-chloroquinazoline (5) and 7-chloro-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidine (7). Treatment of 3a with benzaldehyde (9a) gave benzoin (8a). Similar results were obtained in the reactions of 1,3-dimethyl-2-(α-hydroxybenzyl)imidazolium iodide (4a).

CYANOHYDRINS AS SUBSTRATES IN BENZOIN CONDENSATION. REGIOCONTROLLED MIXED BENZOIN CONDENSATION

O-Benzoylated cyanohydrins of aromatic aldehydes have been used as one of the substrates in the benzoin condensation.They were treated with aromatic aldehydes under phase-transfer conditions to result in benzoin benzoates.By this method aldehydes which fail to undergo condensation using traditional conditions could be converted into benzoins.By the Umpolung of reactivity of the pertinent aldehyde it was possible to prepare both isomeric unsymmetrical benzoins, including the thermodynamically less stable ones.