53478-18-5Relevant articles and documents
An improved synthesis of phosphonomethyl analogues of glyceraldehyde-3-phosphate and dihydroxy-acetone phosphate
Page,Blonski,Perie
, p. 8027 - 8030 (2007/10/02)
Compounds 1 and 2, phosphonate analogues of dihydroxy-acetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GAP) respectively, are easily and quantitatively obtained from diethyl-4,4-diethoxy-3-hydroxybutyl-1-phosphonate 3. Depending upon the acidic conditions utilised for the deprotection of the phosphonate and carbonyl groups, the aldol/ketol rearrangement allows the synthesis of either compound.