53494-57-8

Basic information

• Product Name: (S)-1-Amino-3-chloro-2-propanol
• Synonyms: (S)-1-Amino-3-chloro-2-propanol
• CAS NO: 53494-57-8
• Molecular Formula: C₃H₈ClNO
• Molecular Weight: 109.55
• Mol File: 53494-57-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 240.2°Cat760mmHg
• Flash Point: 99.1°C
• Appearance: /
• Density: 1.203g/cm³
• Vapor Pressure: 0.0067mmHg at 25°C
• Refractive Index: 1.479
• PKA: 11.70±0.35(Predicted)
• CAS DataBase Reference: (S)-1-Amino-3-chloro-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Amino-3-chloro-2-propanol(53494-57-8)
• EPA Substance Registry System: (S)-1-Amino-3-chloro-2-propanol(53494-57-8)

Safety Data

• Hazardous Substances Data: 53494-57-8(Hazardous Substances Data)

Usage

Description

(S)-1-Amino-3-chloro-2-propanol, also known as serinol, is an organic compound characterized by its chemical formula C3H8ClNO. It is a chiral molecule, which means it has two enantiomers: (S)-serinol and (R)-serinol. This clear, colorless to slightly yellow liquid exhibits a mild odor and is recognized for its versatility in various industrial and research applications.

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
(S)-1-Amino-3-chloro-2-propanol is utilized as a fundamental building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and properties make it a valuable component in the development of new drugs and agricultural chemicals.
Used as a Chiral Resolution Reagent:
In the field of chemistry, (S)-1-Amino-3-chloro-2-propanol serves as a chiral resolution reagent. This application is crucial for separating enantiomers, which are molecules that are mirror images of each other but may have different biological activities.
Used in Surfactant and Corrosion Inhibitor Production:
(S)-1-Amino-3-chloro-2-propanol is employed as a precursor in the production of surfactants and corrosion inhibitors. Its role in these industries is essential for creating effective products that can be used in various applications, such as cleaning agents and protective coatings.
Used in Polymer and Plastics Manufacturing:
Furthermore, (S)-1-Amino-3-chloro-2-propanol has applications in the manufacturing of polymers and plastics. Its incorporation into these materials can enhance their properties, such as strength, durability, and resistance to environmental factors.

InChI:InChI=1/C3H8ClNO/c4-1-3(6)2-5/h3,6H,1-2,5H2/t3-/m1/s1

Upstream product

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Downstream Products

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Relevant articles and documents

Environment-friendly synthesis method of linezolid and intermediate thereof

The invention relates to a more environment-friendly synthesis method of linezolid and a key intermediate thereof. The more environment-friendly synthesis method is characterized in that the key intermediate of linezolid is prepared through the steps of hydroxyl protection, carboxyl reduction, hydroxyl halogenation, ring closing, halogenation after hydroxyl deprotection, ring opening and the likeby taking a natural chiral product L-serine as an initial raw material. According to the more environment-friendly synthesis method provided by the invention, a chiral center is introduced by adoptingthe natural chiral product, the reaction yield is high, the technological operation is simple, the product purity is high, and the synthesis method is more environment-friendly and is suitable for industrial production.

Immobilized benzylpenicillin acylase: Application to the synthesis of optically active forms of carnitin and propranalol

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