53515-36-9 Usage
General Description
4-(2-Aminoethyl)thiomorpholine is a chemical compound with the molecular formula C6H14N2S. It is a heterocyclic amine that contains both an amino group and a thiol group within its structure. 4-(2-AMINOETHYL)THIOMORPHOLINE is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. It has also been studied for its potential anticonvulsant and antimicrobial properties. 4-(2-Aminoethyl)thiomorpholine is a versatile and important intermediate in organic synthesis, with potential applications in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 53515-36-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,5,1 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53515-36:
(7*5)+(6*3)+(5*5)+(4*1)+(3*5)+(2*3)+(1*6)=109
109 % 10 = 9
So 53515-36-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H14N2S/c7-1-2-8-3-5-9-6-4-8/h1-7H2/p+2
53515-36-9Relevant articles and documents
Preparation and antitumor activity of additional mitomycin A analogues
Sami,Remers,Bradner
, p. 703 - 708 (2007/10/02)
On the basis of qualitative structure-activity relationships developed in the preceding article, a series of 32 new mitomycin A analogues were prepared and tested in antitumor screens. Seven of them gave greater prolongation of life (ILS) than mitomycin C in the mouse P388 leukemia assay. They included examples with 7-O substituents such as cyclic ethers and nitrogen heterocycles. A Hansch analysis was attempted with log P and MR as the independent variables, but no statistically significant correlation could be made. Seven compounds, chosen mainly for their good potency (MED), were tested in the subcutaneous B16 melanoma assay in mice and four of them showed greater ILS than mitomycin C.
