53617-37-1

Basic information

• Product Name: 4-PYRROLIDIN-3-YLMORPHOLINE
• Synonyms: 4-(3-Pyrrolidinyl)morpholine;3-(Morpholin-4-yl)pyrrolidine;Morpholine, 4-(3-pyrrolidinyl)-;4-(Pyrrolidin-3-yl)
• CAS NO: 53617-37-1
• Molecular Formula: C8H16N2O
• Molecular Weight: 156.23
• Product Categories: pharmacetical
• Mol File: 53617-37-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 241.615 °C at 760 mmHg
• Flash Point: 99.925 °C
• Appearance: /
• Density: 1.063 g/cm³
• Vapor Pressure: 0.036mmHg at 25°C
• Refractive Index: 1.503
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 10.11±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 4-PYRROLIDIN-3-YLMORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PYRROLIDIN-3-YLMORPHOLINE(53617-37-1)
• EPA Substance Registry System: 4-PYRROLIDIN-3-YLMORPHOLINE(53617-37-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 53617-37-1(Hazardous Substances Data)

Usage

Uses

4-(3-Pyrrolidinyl)morpholine is used as pharmaceutical intermediate.

InChI:InChI=1/C8H16N2O/c1-2-9-7-8(1)10-3-5-11-6-4-10/h8-9H,1-7H2

Upstream product

• 216669-62-4 (S)-1-tosyl-3-morpholinopyrrolidine 

Relevant articles and documents

HTT MODULATORS FOR TREATING HUNTINGTON'S DISEASE

Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.

Structure-selectivity relationship in alkyllithium-aldehyde condensations using 3-aminopyrrolidine lithium amides as chiral auxiliaries

A nonracemizing route to a set of chiral 3-aminopyrrolidines, based on 4-hydroxy-(L)-proline, is described. The induction potential of the lithium amides derived from these diamines has then been investigated in the asymmetric addition of alkyllithium com