53631-18-8

Basic information

• Product Name: 2-Bromo-1-(3-fluorophenyl)ethan-1-one
• Synonyms: BUTTPARK 35\01-52;3-FLUOROPHENACYL BROMIDE;ALPHA-BROMO-3-FLUOROACETOPHENONE;2-BROMO-3'-FLUOROACETOPHENONE;2-BROMO-1-(3-FLUOROPHENYL)ETHAN-1-ONE;Ethanone, 2-bromo-1-(3-fluorophenyl)- (9CI);3-Fluorophenacyl bromide 95%;3-Fluorophenacylbromide95%
• CAS NO: 53631-18-8
• Molecular Formula: C₈H₆BrFO
• Molecular Weight: 217.04
• EINECS: 1592732-453-0
• Product Categories: ACETYLHALIDE;Acetophenone series;Fluorine series
• Mol File: 53631-18-8.mol
• Article Data: 52

Chemical Properties

• Melting Point: 34-35
• Boiling Point: 76°C 0,09mm
• Flash Point: 110 °C
• Appearance: /
• Density: 1.568 g/cm³
• Vapor Pressure: 0.0287mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Keep Cold
• Sensitive: Lachrymatory
• CAS DataBase Reference: 2-Bromo-1-(3-fluorophenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-1-(3-fluorophenyl)ethan-1-one(53631-18-8)
• EPA Substance Registry System: 2-Bromo-1-(3-fluorophenyl)ethan-1-one(53631-18-8)

Safety Data

• Hazard Codes: C,Xi
• Statements: 36/37/38-34
• Safety Statements: 26-36/37/39-45-27
• RIDADR: UN 3335
• WGK Germany: 3
• HazardClass: LACHRYMATOR, CORROSIVE
• Hazardous Substances Data: 53631-18-8(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C8H6BrFO/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4H,5H2

Upstream product

• 813414-83-4 1-bromo-2-(meta-fluorophenyl)ethyne 
• 350-51-6 3-fluorostyrene 
• 402-63-1 1-(3-fluorophenyl)ethanol 
• 67-56-1 methanol 
• 455-36-7 1-(3-fluorophenyl)ethanone 

Downstream Products

• 123184-09-8 1-(3-Fluoro-phenyl)-5-methyl-hexane-1,4-dione 
• 129486-41-5 4-(3-fluorophenyl)-2-<<4(5)-methyl-5(4)-imidazolyl>methyl>thiazole 
• 929561-25-1 C₁₆H₉BrF₄N₂S*ClH 
• 929561-26-2 C₁₆H₉F₅N₂S*ClH 
• 776285-86-0 C₁₆H₁₀F₄N₂S 
• 1440434-94-5 2-(3,4-dimethylphenoxy)-N-(4-(3-fluorophenyl)thiazol-2-yl)acetamide 
• 455-37-8 3-fluorobenzamide 
• 1390058-29-3 N-(4-(3-fluorophenyl)thiazol-2-yl)-2-p-tolylacetamide 

Relevant articles and documents

Thiazole ring-containing amide compounds as well as preparation method and application thereof

The invention discloses thiazole ring-containing amide compounds as well as a preparation method and application thereof, and belongs to the field of chemical technologies and pesticides. According to the present invention, p-phenylenediamine is adopted as a raw material to synthesize a series of the thiazole ring-containing amide compounds, and the synthesized thiazole ring-containing amide compounds have good inhibition effects on Xanthomonas oryzae pv.Oryza (Xoo), Xanthomonas oryzae pv.Oryzcola (Xoc) and Xanthomonas axonophora pv.Citri (Xac) in agricultural diseases and insect pests, and can be used for preparing the anti-plant bacterium agent.

High Chemo-/Stereoselectivity for Synthesis of Polysubstituted Monofluorinated Pyrimidyl Enol Ether Derivatives

A novel intramolecular Smiles rearrangement of α-fluoro-β-keto-pyrimidylsulfones (usually used as a carbon nucleophile) was developed, providing a versatile avenue for synthesis of tri/tetra-substituted monofluorinated pyrimidyl enol ethers. Among these, diverse (Z)-monofluorovinylsulfones and sulfinates were efficiently assembled by adding extra electrophile and fine-tuning reaction conditions. The process is triggered by a keto-enol tautomerism from enol oxyanion to pyrimidine 2-carbon, completely different from the classical carbon nucleophilic addition reaction approach.

Chiral Bidentate Phosphoramidite-Pd Catalyzed Asymmetric Decarboxylative Dipolar Cycloaddition for Multistereogenic Tetrahydrofurans with Cyclic N-Sulfonyl Ketimine Moieties

An asymmetric [3 + 2] cycloaddition of vinyl ethylenecarbonates (VECs) and (E)-3-arylvinyl substituted benzo[d] isothiazole 1,1-dioxides has been developed using the Pd complex of a bidentate phosphoramidite (Me-BIPAM) as the catalyst, providing a wide variety of chiral multistereogenic vinyltetrahydrofurans in good yields with excellent diastereo- and enantioselectivities (up to >20:1 dr, 99% ee).