5365-15-1

Basic information

• Product Name: 2,2-DICHLOROCYCLOPROPANECARBONYL CHLORIDE
• Synonyms: Cyclopropanecarbonyl chloride, 2,2-dichloro-
• CAS NO: 5365-15-1
• Molecular Formula: C₄H₃Cl₃O
• Molecular Weight: 173.43
• Mol File: 5365-15-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-DICHLOROCYCLOPROPANECARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DICHLOROCYCLOPROPANECARBONYL CHLORIDE(5365-15-1)
• EPA Substance Registry System: 2,2-DICHLOROCYCLOPROPANECARBONYL CHLORIDE(5365-15-1)

Safety Data

• Hazardous Substances Data: 5365-15-1(Hazardous Substances Data)

Usage

General Description

2,2-Dichlorocyclopropanecarbonyl chloride is a highly reactive chemical compound that is used in the production of various pharmaceuticals and agrochemicals. It is also utilized as a building block in organic synthesis to create complex molecules. This colorless liquid has a pungent odor and is highly toxic, flammable, and corrosive. It must be handled with extreme caution and stored in a well-ventilated area away from heat and ignition sources. In the presence of moisture, it can release toxic gases and cause severe skin and eye irritation. Therefore, proper safety measures and protective equipment are necessary when working with this chemical.

Upstream product

• 5365-14-0 2,2-dichlorocyclopropanecarboxylic acid 

Downstream Products

• 75885-60-8 2,2-dichlorocyclopropanecarboxamide 
• 61-33-6 penicillin G 
• 176041-73-9 2,2-dichlorocyclopropyl isocyanate 
• 36159-76-9 4-phenyl-1-naphthol 
• 56058-22-1 1-Benzoyl-2,2-dichlorocyclopropane 
• 82789-63-7 1-(2,4,6-trimethylbenzoyl)-2,2-dichlorocyclopropane 
• 95650-81-0 1-(4-methoxybenzoyl)-2,2-dichlorocyclopropane 
• 61971-73-1 2,2-dichlorocyclopropyl methyl ketone 

Relevant articles and documents

Mechanism-based inactivation of α-chymotrypsin

The peptidyl ester derivatives of 2,2-dichlorocyclopropanol and the amide derivative of 2,2-dichlorocyclopropylamine were prepared as novel mechanism-based inactivators of α-chymotrypsin. The esters inactivated α-chymotrypsin irreversibly but the amide did not show any irreversible inhibitory activity toward α-chymotrypsin.

N,N-Dialkyl-4-oxoalkanamides from gem-Dichlorocyclopropyl Ketones

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6-(Substituted-cycloalkylcarboxamide) penicillanic acids

Penicillins of the formula SPC1 Or a pharmaceutically-acceptable, nontoxic salt thereof, Wherein R1 and R2 are the same or different and each is hydrogen, fluorine, chlorine or bromine; or when R2 is hydrogen, R1 can also be cyano, hydroxyl, azido, amino or nitro; or R1 and R2 are bonded to a ring carbon atom and constitute a single oxygen atom; R3 is hydrogen, methyl, chlorine, bromine, cyano, methoxy or carboxyl; and n is 2 to 7; Are useful for their antibacterial activity.