53661-19-1

Basic information

• Product Name: 3-amino-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
• Synonyms: 3-Amino-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile; 4-isoquinolinecarbonitrile, 3-amino-5,6,7,8-tetrahydro-
• CAS NO: 53661-19-1
• Molecular Formula: C₁₀H₁₁N₃
• Molecular Weight: 173.2144
• Mol File: 53661-19-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 358.9°C at 760 mmHg
• Flash Point: 170.9°C
• Density: 1.21g/cm³
• Vapor Pressure: 2.46E-05mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 3-amino-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile(53661-19-1)
• EPA Substance Registry System: 3-amino-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile(53661-19-1)

Safety Data

• Hazardous Substances Data: 53661-19-1(Hazardous Substances Data)

Upstream product

• 4354-73-8 2-(cyclohexylidene)malononitrile 
• 88745-29-3 1-Dicyanomethylene-2-N,N-dimethylaminomethylenecyclohexane 

Downstream Products

• 137676-51-8 3-Amino-4-carbethoxy-5,6-dihydro-7H-2-pyrindine 
• 69958-52-7 5,6,7,8-tetrahydroisoquinolin-3-amine 
• 130688-32-3 3-amino-4-carbamido-6,7,8,9-tetrahydroisoquinoline 
• 130688-31-2 3-Amino-4-carboxy-5,6,7,8-tetrahydroisochinoline 
• 88745-30-6 3-Amino-6,7-dihydro-5H-<2>pyrindin-4-carbonitril 

Relevant articles and documents

ACETALS OF LACTAMS AND ACID AMIDES. 39. SYNTHESIS OF THREE-RING DERIVATIVES OF PYRIDOPYRIMIDINES ON THE BASIS OF THE REACTION OF DIMETHYLFORMAMIDE ACETAL WITH DICYANOMETHYLENECYCLOALKANES

The reaction of dicyanomethylenecyclopentane and -cyclohexane with dimethylformamide diethylacetal was used to synthesize dieneamino nitriles, from which isoquinoline and 2-pyridine derivatives were obtained by treatment with ammonia.The reaction of 3-ami