536724-67-1

Basic information

• Product Name: Umicore M2
• Synonyms: Tricyclohexylphosphine[3-phenyl-1H-inden-1-ylidene][1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene]ruthenium(II) dichloride, min. 95%;Tricyclohexylphosphine[3-phenyl-1H-inden-1-ylidene][1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene]ruthenium (II) dichloride, min. 95%;Tricyclohexylphosphine[3-phenyl-1H-inden-1-ylidene][1,3-bis(2,4,6-triMethylphenyl)-4,5-dihydroiMidazol-2-ylidene]rutheniuM(II),95%;RutheniuM, [1,3-bis(2,4,6-triMethylphenyl)-2-iMidazolidinylidene]dichloro(3-phenyl-1H-inden-1-ylidene)(tricyclohexylphosphine)-, (SP-5-41)-;Umicore M 2;(SP-5-41)-[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(3-phenyl-1H-inden-1-ylidene)(tricyclohexylphosphine)ruthenium;UMicore M2, 10% Ru, Product of UMicore;Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](3-phenyl-1H-inden-1-ylidene)(tricyclohexylphosphine)ruthenium(II)
• CAS NO: 536724-67-1
• Molecular Formula: C₅₄H₆₉Cl₂N₂PRu
• Molecular Weight: 949.103
• Product Categories: metal carbene complex;Ru
• Mol File: 536724-67-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 159 (d)-162°C
• Appearance: dark red/Powder
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Umicore M2(CAS DataBase Reference)
• NIST Chemistry Reference: Umicore M2(536724-67-1)
• EPA Substance Registry System: Umicore M2(536724-67-1)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/38
• Safety Statements: 26-24/25
• WGK Germany: 3
• Hazardous Substances Data: 536724-67-1(Hazardous Substances Data)

Usage

Description

Umicore M2 is a versatile and efficient catalyst that plays a significant role in various chemical reactions and processes. It is known for its ability to facilitate cross-metathesis reactions and is also utilized in the preparation of Weinreb amide pyrrolidines. The chemical properties of Umicore M2 include its distinctive red powder appearance.

Uses

Used in Chemical Synthesis Industry:
Umicore M2 is used as a catalyst for cross-metathesis reactions, which are essential in the synthesis of various complex organic molecules. Its application in this industry is crucial for the development of new pharmaceuticals, agrochemicals, and advanced materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Umicore M2 is used in the preparation of Weinreb amide pyrrolidines. These compounds serve as key intermediates in the synthesis of various bioactive molecules, including potential drug candidates for the treatment of various diseases.
Used in Catalyst Research and Development:
Umicore M2's unique properties make it an interesting subject for research and development in the field of catalysis. Its potential applications in various chemical reactions and processes can be further explored and optimized, leading to the development of more efficient and sustainable chemical processes.

Reactions

Catalyst used for the Atom Transfer Radical Polymerization (ATRP) of vinyl monomers.

Upstream product

• 172222-30-9 bis(tricyclohexylphosphine)-3-phenyl-1H-inden-1-ylidene ruthenium(II) dichloride 
• 173035-10-4 1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazolium chloride 

Relevant articles and documents

Preparation of epothilone derivatives

The invention comprises a novel process for the preparation of an epothilone derivative of formula I: wherein R1 and R2 independently from each other represent hydrogen or protecting groups and R3 is methyl or trifluoromet