5369-55-1

Basic information

• Product Name: 2,4-Diphenylfuran
• Synonyms: 2,4-Diphenylfuran
• CAS NO: 5369-55-1
• Molecular Formula: C₁₆H₁₂O
• Molecular Weight: 220.26588
• Mol File: 5369-55-1.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 351.8°Cat760mmHg
• Flash Point: 169.9°C
• Appearance: /
• Density: 1.086g/cm³
• Vapor Pressure: 8.14E-05mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: 2,4-Diphenylfuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Diphenylfuran(5369-55-1)
• EPA Substance Registry System: 2,4-Diphenylfuran(5369-55-1)

Safety Data

• Hazardous Substances Data: 5369-55-1(Hazardous Substances Data)

Usage

Description

2,4-diphenylfuran is a diphenylfuran derivative with phenyl groups located at positions 2 and 4 on the furan ring. It is an organic compound that belongs to the class of furans, which are heterocyclic compounds containing a four-membered ring with one oxygen atom.

Uses

Used in Pharmaceutical Industry:
2,4-diphenylfuran is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential applications in treating different diseases.
Used in Chemical Industry:
In the chemical industry, 2,4-diphenylfuran can be utilized as an intermediate in the production of other organic compounds, such as dyes, pigments, and polymers. Its versatile structure makes it a valuable component in the synthesis of a wide range of materials.
Used in Research and Development:
2,4-diphenylfuran is also used as a research compound in academic and industrial laboratories. Its properties and reactivity are studied to gain insights into the behavior of furan-based compounds and to develop new methodologies for their synthesis and application.

InChI:InChI=1/C16H12O/c1-3-7-13(8-4-1)15-11-16(17-12-15)14-9-5-2-6-10-14/h1-12H

Upstream product

• 495-45-4 dypnone 
• 98-95-3 nitrobenzene 
• 5031-83-4 2,4-diphenylcrotonaldehyde 
• 70-11-1 α-bromoacetophenone 
• 31428-82-7 (Z)-2-bromo-1-phenylvinyl diethyl phosphate 
• 98-86-2 acetophenone 
• 31327-17-0 (Z)-2-chloro-1-phenylvinyl diethyl phosphate 
• 93-97-0 benzoic acid anhydride 
• 69814-23-9 4-oxo-2,4-diphenylbutanal 
• 94-41-7 benzalacetophenone 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 536-74-3 phenylacetylene 
• 58294-83-0 2,4-diphenyl-but-3-yne-1,2-diol 
• 7462-71-7 4-bromo-1,3-diphenyl-2-buten-1-one 

Downstream Products

• 959-27-3 (Z)-1,4-diphenylbut-2-ene-1,4-dione 
• 576169-89-6 3,5-diphenyl-furan-2-carboxylic acid 
• 1623145-23-2 (3,5-diphenylfuran-2-yl)trimethylsilane 
• 1623146-16-6 C₂₃H₂₆O₄Si 
• 1623145-56-1 (R)-ethyl 2-(3,5-diphenylfuran-2-yl)-3,3,3-trifluoro-2-hydroxypropanoate 
• 924645-22-7 3,5-diphenylfuran-2-carbonitrile 

Relevant articles and documents

Me3SiBr-mediated intramolecular cyclization of γ-functionalized trimethylsilyl nitronates

The silylation of nitro compounds of general formula X1X2CHCH(Ar)CH2NO2 with Me3SiBr/Et3N at -30°C leads to hitherto unknown 2-(N,N'-bis(trimethylsilyloxy)amino-2,3-dihydrofurans (X1/

CATALYTIC METHOD OF SYNTHESIS OF 2,4-DIPHENYLFURAN AND 2-PHENYLINDOLE

2,4-Diphenylfuran has been obtained from acetophenone and its mixture with aniline, over K-16 catalyst.It has been established that the reaction proceeds through a stage of dypnone formation.When the aniline-acetophenone mixture is used as the starting material, small amounts of 2-phenylindole are formed.

Access to Benzylic Quaternary Carbons from Aromatic Ketones

The construction of benzylic all-carbon quaternary stereocenters, which are ubiquitous in biomolecules and drugs, is a task of high practical significance. Herein, we disclose a highly efficient one-pot method of constructing all-carbon quaternary structu

Suzuki-Miyaura cross-coupling reaction of 1,2-oxaborol-2(5H)-ols with carboxylic anhydrides: A new method to furans

An efficient one-step method has been developed to construct furans via a Suzuki-Miyaura cross-coupling reaction of 1,2-oxaborol-2(5H)-ols with carboxylic anhydrides. In the presence of Pd(OAc)2/PCy3, the multi-substituted alkenylboron compounds could couple with anhydrides to obtain furans in moderate-to-good yields. The addition of bases promoted the coupling reaction, and the plausible reaction mechanism was proposed.