53700-95-1

Basic information

• Product Name: 4,5-DIMETHYL-1H-PYRROLE-2-CARBOXALDEHYDE
• Synonyms: 4,5-DIMETHYL-1H-PYRROLE-2-CARBOXALDEHYDE;4,5-Dimethyl-1H-pyrrole-2-carbaldehyde
• CAS NO: 53700-95-1
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• Mol File: 53700-95-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 242.9°C at 760 mmHg
• Flash Point: 106.9°C
• Appearance: /
• Density: 1.099g/cm³
• Vapor Pressure: 0.033mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4,5-DIMETHYL-1H-PYRROLE-2-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIMETHYL-1H-PYRROLE-2-CARBOXALDEHYDE(53700-95-1)
• EPA Substance Registry System: 4,5-DIMETHYL-1H-PYRROLE-2-CARBOXALDEHYDE(53700-95-1)

Safety Data

• Hazardous Substances Data: 53700-95-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H9NO/c1-5-3-7(4-9)8-6(5)2/h3-4,8H,1-2H3

Upstream product

• 600-28-2 2,3-dimethyl-1H-pyrrole 
• 74-90-8 hydrogen cyanide 
• 925-90-6 ethylmagnesium bromide 
• 124647-47-8 N-(hydroxy-2' ethyl) amino-3 methyl-2 butene-2 oate d'ethyle 
• 3284-47-7 ethyl 3-methyl-1H-pyrrole-2-carboxylate 
• 68-12-2 N,N-dimethyl-formamide 
• 63900-79-8 4,5-dimethyl-pyrrole-2,3-dicarboxylic acid-3-ethyl ester 
• 860759-76-8 4,5-dimethyl-1H-pyrrole-3-carboxylic acid 

Downstream Products

• 186610-95-7 (3Z)-[(4,5-dimethyl-1H-pyrrol-2-yl)-methylidenyl]-indolin-2-one 

Relevant articles and documents

Highly regio-and enantioselective synthesis of polysubstituted 2 H -pyrroles via pd-catalyzed intermolecular asymmetric allylic dearomatization of pyrroles

A highly efficient synthesis of chiral polysubstituted 2H-pyrrole derivatives via a Pd-catalyzed intermolecular asymmetric allylic dearomatization reaction of pyrroles is presented. With the commercially available palladium precursor and chiral ligand, the polysubstituted 2H-pyrrole products containing a chiral quaternary carbon center were obtained with up to 97% ee and >95/5 regioselectivity.

SYNTHESE DE PYRROLES ET D'OXAZOLES PAR PYROLYSE DE N-(HYDROXY-2' ETHYL) AMINO-3 PROPENOATE

The gas phas pyrolysis of various N-(2'-hydroxyethyl)-3-amino propenoates 1-6 and N-(2'-hydroxy-2'-phenyl ethyl)-3-amino propanoate 7-9 at 390 deg C-420 deg C leads respectively to formylpyrroles 11-16 and benzoylpyrroles 17-19 and, in some cases, to substituted oxazoles 36-39.The results are best explained by the intermediate formation of a dicarbonyl derivative followed either by an intramolecular thermal crotonisation or a six ? electrocyclization of an azomethine ylide.