5382-47-8

Basic information

• Product Name: QUINOLINE-6-CARBOHYDRAZIDE
• Synonyms: QUINOLINE-6-CARBOHYDRAZIDE;6-quinolinecarbohydrazide;quinoline-6-carbohydrazide(SALTDATA: FREE);6-Quinolinecarbohydrazide , tech;6QuinolCON2;6-Quinolinecarboxylic acid hydrazide
• CAS NO: 5382-47-8
• Molecular Formula: C₁₀H₉N₃O
• Molecular Weight: 187.2
• Mol File: 5382-47-8.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Density: 1.297g/cm³
• Refractive Index: 1.682
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: QUINOLINE-6-CARBOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: QUINOLINE-6-CARBOHYDRAZIDE(5382-47-8)
• EPA Substance Registry System: QUINOLINE-6-CARBOHYDRAZIDE(5382-47-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5382-47-8(Hazardous Substances Data)

Usage

General Description

Quinoline-6-carbohydrazide is a chemical compound with the molecular formula C10H9N3O. It is a derivative of quinoline and is commonly used in the synthesis of various pharmaceuticals, dyes, and agrochemicals. Quinoline-6-carbohydrazide is known for its versatile reactivity and is often employed as a precursor in the preparation of heterocyclic compounds. It is also used as a building block in organic synthesis, particularly in the development of novel drugs and advanced materials. Additionally, quinoline-6-carbohydrazide has potential applications in the field of medicinal chemistry due to its pharmacological and bioactive properties. Overall, this compound plays a significant role in the production of a wide range of valuable products in various industries.

InChI:InChI=1/C10H9N3O/c11-13-10(14)8-3-4-9-7(6-8)2-1-5-12-9/h1-6H,11H2,(H,13,14)

Upstream product

• 73987-38-9 quinoline-6-carboxylic acid ethyl ester 
• 38896-30-9 6-(methoxycarbonyl)quinoline 
• 10349-57-2 Quinoline-6-carboxylic acid 

Downstream Products

• 858784-67-5 N-(quinoline-6-carbonyl)-N'-(toluene-4-sulfonyl)-hydrazine 
• 866018-92-0 u202fN'-(thiophen-2-ylmethylene)quinoline-6-carbohydrazide 

Relevant articles and documents

Synthesis of novel quinoline-based thiadiazole, evaluation of their antileishmanial potential and molecular docking studies

New series of quinoline-based thiadiazole analogs (1–20) were synthesized, characterized by EI-MS, 1H NMR and 13C NMR. All synthesized compounds were subjected to their antileishmanial potential. Sixteen analogs 1–10, 12, 13, 16, 17,

Synthesis of quinoline derivatives as diabetic II inhibitors and molecular docking studies

In searchof the potenttherapeutic agent as an α-glucosidase inhibitor, we have synthesized twenty-five analogs (1–25) of quinoline-based Schiff bases as an inhibitoragainst α-glucosidase enzyme under positive control acarbose (IC50 = 38.45 ± 0.

Access to a new class of biologically active quinoline based 1,2,4-triazoles

As an aspect of our ongoing research in search of new antimicrobial armamentarium, a series of 1,2,4-triazol-3-ylthio-acetamides was constructed and in vitro analyzed for their antimicrobial activity against several bacteria and fungi. Aiming to establish an increased potency, the bioassay results were matched to those of 1,3,4-oxadiazoles, utilized previously. Remarkably, 1,2,4-triazoles were found to possess a good spectrum of antifungal potency, which eventually suggested the azole template as an essential pharmacophore to diversify the biological occupations of the attendant molecules. However, it was noticed that the potency of final analogs against each strain placed reliance on the type of substituent present on benzothiazole ring. The structures of final compounds were confirmed with the aid of IR, 1H NMR, 13C NMR spectroscopy and CHN analysis.