53821-00-4

Basic information

• Product Name: benzyl (2-chlorophenyl)carbamate
• Synonyms: benzyl (2-chlorophenyl)carbamate
• CAS NO: 53821-00-4
• Molecular Weight: 261.708
• Mol File: 53821-00-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl (2-chlorophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2-chlorophenyl)carbamate(53821-00-4)
• EPA Substance Registry System: benzyl (2-chlorophenyl)carbamate(53821-00-4)

Safety Data

• Hazardous Substances Data: 53821-00-4(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 62-53-3 aniline 
• 3422-02-4 N-(benzyloxycarbonyl)aniline 
• 95-51-2 o-chloroaniline 

Downstream Products

• 3320-83-0 o-chlorophenyl isocyanate 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Metal-free late-stage C(sp2)-H functionalization of: N -aryl amines with various sodium salts

Metal-free consecutive C(sp2)-X (X = Cl, Br, S, N) bond formations of N-aryl amines (cyclic, fused, carbamate, and aminium radicals) were achieved under mild conditions using [bis(trifluoroacetoxy)iodo]benzene (PIFA) and simple nonharmful sodium salts. This direct and selective C(sp2)-H functionalization showed excellent functional group compatibility, cost effectiveness, and late-stage applicability for the synthesis of biologically active natural products. Two mechanisms were proposed to explain the ortho- or para-preference, as well as the accelerating effect of CH3NO2