5384-54-3Relevant articles and documents
Stereoselective synthesis of new classes of atropisomeric compounds through a tandem Michael reaction-azacyclization process. Part 2
Le Gac, Stephane,Monnier-Benoit, Nicolas,Metoul, Lionel Doumampouom,Petit, Samuel,Jabin, Ivan
, p. 139 - 145 (2007/10/03)
Three new classes of atropisomeric compounds, that is, 6-aryl-dihydro- pyridin-2-ones, 6-aryl-pyridin-2-ones and 2-aryl-pyrroles, have been prepared from chiral imines through an efficient stereoselective tandem Michael-azacyclization process. In all cases, a study has shown that the barrier to rotation of the chiral axis is remarkably high.