5393-69-1

Basic information

• Product Name: 2-ethoxypropanal
• Synonyms: 2-Ethoxypropanal; Ethoxy propionaldehyde; propanal, 2-ethoxy-
• CAS NO: 5393-69-1
• Molecular Formula: C₅H₁₀O₂
• Molecular Weight: 102.1317
• Mol File: 5393-69-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 93.9°C at 760 mmHg
• Density: 0.887g/cm³
• Vapor Pressure: 48.4mmHg at 25°C
• Refractive Index: 1.386
• CAS DataBase Reference: 2-ethoxypropanal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxypropanal(5393-69-1)
• EPA Substance Registry System: 2-ethoxypropanal(5393-69-1)

Safety Data

• Hazardous Substances Data: 5393-69-1(Hazardous Substances Data)

Upstream product

• 12150-46-8 1,1'-bis-(diphenylphosphino)ferrocene 
• 109-92-2 ethyl vinyl ether 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Linear-selective hydroformylation of vinyl ether using Rh (acac)(2,2′-bis{(di[1H-indol-1-yl]phosphanyl)oxy}-1,1′-binaphthalene) – Possible way to synthesize 1,3-propanediol

Three bidentate phosphoramidite ligands were synthesized, characterized, and employed in Rh-catalyzed hydroformylation of vinyl ethers. The complex Rh(acac)(2,2′-bis{(di[1H-indol-1-yl]phosphanyl)oxy}-1,1′-binaphthalene} (acac = acetylacetone) (Rh-L4) was also synthesized and characterized. Rh-L4 showed good regioselectivity for the hydroformylation of vinyl ethers under mild reaction conditions: 2 MPa of syngas, 1:1 (H2/CO) substrate/catalyst molar ratio 1000:1, and 60 °C. The linear selectivity was up to 98%, and in most cases was about 80%, with no hydrogenation product formation observed, which could be a potential way to synthesize 1,3-propanediol. A mechanism study including density functional theory computational analysis showed that both Rh–H and CO insertion steps in the hydroformylation of vinyl ether were linear-preferred in our catalyst system.

Process for synthesis of acrylic acid precursors via hydroformylation of vinyl ether

A process is disclosed for the preparation of acrylic acid precursors by a hydroformylation process which comprises reacting a vinyl ether with carbon monoxide and hydrogen in the presence of a catalyst comprising a rhodium carbonyl compound and a phosphine ligand at a mild temperature and pressure until there is substantial formation of the intermediate 2- and 3-ethoxypropanals, followed by oxidation of said aldehydes and pyrolysis to said acrylic acid.