5394-23-0Relevant articles and documents
A novel photosensitizer based on a ruthenium(ii) phenanthroline bis(perylenediimide) dyad: synthesis, generation of singlet oxygen and in vitro photodynamic therapy
Aksakal, Nuray Esra,Kazan, Hasan Hüseyin,E?ik, Esra Tanriverdi,Yuksel, Fatma
, p. 17538 - 17545 (2018/10/31)
In this study, a novel photosensitizer having two perylenediimide units and a phenanthroline ruthenium(ii) coordination moiety (Ru-BP) has been developed for photodynamic therapy (PDT) of cancer cells. This new compound was prepared via reactions of two n
Copper-catalyzed N-arylation of imidazoles and benzimidazoles
Altman, Ryan A.,Koval, Erica D.,Buchwald, Stephen L.
, p. 6190 - 6199 (2008/02/10)
(Chemical Equation Presented) 4,7-Dimethoxy-1,10-phenanthroline (L1c) was found to be an efficient ligand for the copper-catalyzed N-arylation of imidazoles and benzimidazoles with both aryl iodides and bromides under mild conditions. Further optimization of the system has revealed that the addition of poly(ethylene glycol) accelerates this reaction. A variety of hindered and functionalized imidazoles, benzimidazoles, and aryl halides were transformed in good to excellent yields. Heteroaryl halides were also coupled in moderate to good yields. We also present the results obtained from a series of coupling reactions, which directly compare the use of L1c with other recently reported ligands.
The synthesis of aromatic diazatricycles from phenylenediamine-bis(methylene Meldrum's acid) derivatives
Graf, Gabriele Ina,Hastreiter, Daniel,Da Silva, Luiz Everson,Rebelo, Ricardo Andrade,Montalban, Antonio Garrido,McKillop, Alexander
, p. 9095 - 9100 (2007/10/03)
The thermocyclisation of phenylenediamine-bis(methylene Meldrum's acid) derivatives has been investigated. Those of o-phenylenediamines give 1,10-phenanthroline derivatives, while those of m- and p-phenylenediamines lead to the preferential formation of angular diazatricycles. Thus, for example, the di-Meldrum's acid derivative of 2,5-dichloro-1,4-phenylenediamine gives, via ipso-substitution, the unexpected angular product 19.