54006-08-5

Basic information

• Product Name: Phosphonic acid, [(2-nitrophenyl)methyl]-, dimethyl ester
• CAS NO: 54006-08-5
• Molecular Formula: C9H12NO5P
• Molecular Weight: 245.172
• Mol File: 54006-08-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(2-nitrophenyl)methyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(2-nitrophenyl)methyl]-, dimethyl ester(54006-08-5)
• EPA Substance Registry System: Phosphonic acid, [(2-nitrophenyl)methyl]-, dimethyl ester(54006-08-5)

Safety Data

• Hazardous Substances Data: 54006-08-5(Hazardous Substances Data)

Upstream product

• 88-72-2 1-methyl-2-nitrobenzene 
• 868-85-9 Dimethyl phosphite 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 121-45-9 phosphorous acid trimethyl ester 

Downstream Products

• 54006-10-9 dimethyl 2-aminobenzylphosphonate 

Relevant articles and documents

Synthesis of P-Substituted 5- And 6-Membered Benzo-Phostams: 2,3-Dihydro-1 H-1,2-benzazaphosphole 2-Oxides and 2,3-Tetrahydro-1 H-1,2-benzazaphosphinine 2-Oxides

Several approaches were developed for the preparation of phosphorus-substituted 5- and 6-membered benzophostams. Carbodiimide-promoted cyclization of zwitterionic aminophosphinates derived from a nitrobenzene precursor accomplished the cyclization in good

Organphosphorus Compounds. XVIII. Synthesisi of 2-Phenyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-Sulfide by Pyrolysis of (2-Aminobenzyl)phenyldithiophosphonic Acid

Reaction of 2-phthalimidobenzyl bromide (12b) with the dialkyl phenylphosphonites (13a-c) afforded the corresponding alkyl phosphinates (14a-c) which upon hydrazinolysis yielded the respective (2-aminobenzyl)phenylphosphinates (16a-c).Reduction of the phosphinates (16a) or (16b) with lithium aluminium hydride gave (2-aminobenzyl)phenylphosphine (15), characterized by its conversion into crystalline 2,3-diphenyl-1,2,3,4-tetrahydro-1,3-benzazaphosphorine (18). (2-Aminobenzyl)phenylphosphine (15) was heated with sulfur in benzene under reflux for 30 min to give 80percent of (2-aminobenzyl)phenyldithiophosphinic acid (20) which when heated between 100-200 deg in vacuum underwent elimination of hydrogen sulfide to yield 2-phenyl-2,3-dihydro-1H-1,2-benzazaphosphole 2-sulfide (22a).Several other new phosphorus compounds are described.An attempt to prepare a 1H-1,2-benzazaphosphole derivative by photolysis of methyl benzylphosphonic azide (7) was unsuccessful.