54030-32-9 Usage
Description
4-Hydroxy-3-(hydroxymethyl)benzaldehyde, also known as A514501, is an organic compound that serves as an impurity in the production of Albuterol, a bronchodilator and tocolytic medication. 4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE is characterized by its chemical structure, which features a benzene ring with hydroxyl and aldehyde functional groups, as well as a hydroxymethyl group attached to the benzene ring. Its unique structure endows it with various applications in different industries.
Uses
Used in Pharmaceutical Industry:
4-Hydroxy-3-(hydroxymethyl)benzaldehyde is used as an impurity in the production of Albuterol, a β2-adrenoceptor agonist, which is a bronchodilator and tocolytic. It helps in the treatment of asthma, chronic obstructive pulmonary disease (COPD), and other respiratory conditions by relaxing the muscles in the airways and improving breathing.
Used in the Preparation of Cinnamyl Alcohol-like Compounds:
In the field of medicine, 4-Hydroxy-3-(hydroxymethyl)benzaldehyde is used in the preparation of Cinnamyl alcohol-like compounds. These compounds have potential therapeutic applications for the treatment of free radical generated related diseases, including auto-immune deficiency diseases. They work by neutralizing free radicals and reducing oxidative stress, which can contribute to the development and progression of various diseases.
Used as a Reagent in the Synthesis of 5-Diacetoxymethyl-cycloSal-d4TMP:
4-Hydroxy-3-(hydroxymethyl)benzaldehyde is also utilized as a reagent in the synthesis of 5-Diacetoxymethyl-cycloSal-d4TMP, a prototype of enzymatically activated cycloSal-pronucleotides. These compounds have shown potential antiviral activities against HIV, making them a valuable tool in the development of new treatments for this viral infection.
Check Digit Verification of cas no
The CAS Registry Mumber 54030-32-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,0,3 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 54030-32:
(7*5)+(6*4)+(5*0)+(4*3)+(3*0)+(2*3)+(1*2)=79
79 % 10 = 9
So 54030-32-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H8O3/c9-4-6-1-2-8(11)7(3-6)5-10/h1-4,10-11H,5H2
54030-32-9Relevant articles and documents
SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES
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, (2019/11/12)
The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
BIOFILM FORMATION INHIBITOR
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Paragraph 0054, (2019/01/06)
PROBLEM TO BE SOLVED: To provide a substance that can effectively inhibit biofilm formation. SOLUTION: A biofilm formation inhibitor has a compound represented by the following formula (I) as an active ingredient (where R1, R2, Rsup
Enzymatically activated cycloSal-d4T-monophosphates: The third generation of cycloSal-pronucleotides
Gisch, Nicolas,Balzarini, Jan,Meier, Chris
, p. 1658 - 1667 (2008/01/27)
The third generation of cycloSal-pronucleotides, 5-diacetoxymethyl- cycloSal-d4T-monophosphates (5-di-AM-cycloSal-d4TMPs), is reported as a new class of "lock-in"-modified cycloSal-pronucleotides. These compounds bear an esterase-cleavable geminal dicarboxylate (acylal) attached to the aromatic ring of the saligenyl unit. The conversion into a strong acceptor group (aldehyde) leads to a strong decrease in hydrolytic stability. As a consequence, a fast release of a nucleoside monophosphate (i.e., d4TMP) follows. The concept of this enzymatic activation is proven by hydrolysis studies in phosphate buffer, cell extracts, and human serum. These investigations showed the conversion of the acylal group into a polar aldehyde by enzymatic cleavage. Besides, antiviral activities against HIV are presented.
