540516-28-7 Usage
General Description
2-(Hydroxymethyl)-5-bromo-1H-benzoimidazole is a chemical compound with the molecular formula C8H7BrN2O. It is a derivative of benzoimidazole, a heterocyclic aromatic organic compound. This chemical is a benzimidazole derivative with a hydroxymethyl group and a bromine atom attached to the benzene ring. It has the potential to be used as a building block for the synthesis of various pharmaceutical compounds and agrochemicals. Additionally, its unique structure and properties make it an interesting target for research in the fields of medicinal and organic chemistry. This chemical may have potential applications in the development of new drugs and agricultural products.
Check Digit Verification of cas no
The CAS Registry Mumber 540516-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,0,5,1 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 540516-28:
(8*5)+(7*4)+(6*0)+(5*5)+(4*1)+(3*6)+(2*2)+(1*8)=127
127 % 10 = 7
So 540516-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrN2O/c9-5-1-2-6-7(3-5)11-8(4-12)10-6/h1-3,12H,4H2,(H,10,11)
540516-28-7Relevant articles and documents
Sustainable Synthesis of 2-Hydroxymethylbenzimidazoles using D-Fructose as a C2 Synthon
Raja, Dineshkumar,Philips, Abigail,Sundaramurthy, Devikala,Chandru Senadi, Gopal
supporting information, p. 3754 - 3759 (2021/10/14)
D-fructose, a biomass-derived carbohydrate has been identified as an environmentally benign C2 synthon in the preparation of synthetically useful 2-hydroxymethylbenzimidazole derivatives by coupling with 1,2-phenylenediamines. Proof of concept was established by synthesizing 23 examples using BF3.OEt2 (20 mol%), TBHP (5.5 M, decane) (1.0 equiv.) in CH3CN at 90 °C for 1 h. The pivotal features of this method include metal-free conditions, short time, good functional group tolerance, gram scale feasibility and the synthesis of benzimidazole fused 1,4-oxazine. Control studies with conventional C2 synthons did not produce the desired product, thus suggesting a new reaction pathway from D-fructose.
