540751-00-6

Basic information

• Product Name: 7-methoxy-3-phenylbenzo[d]isoxazole
• Synonyms: 7-methoxy-3-phenylbenzo[d]isoxazole
• CAS NO: 540751-00-6
• Molecular Weight: 225.247
• Mol File: 540751-00-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-methoxy-3-phenylbenzo[d]isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methoxy-3-phenylbenzo[d]isoxazole(540751-00-6)
• EPA Substance Registry System: 7-methoxy-3-phenylbenzo[d]isoxazole(540751-00-6)

Safety Data

• Hazardous Substances Data: 540751-00-6(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 108-86-1 bromobenzene 
• 6812-16-4 2-Hydroxy-3-methoxybenzonitrile 
• 698-16-8 benzohydroximoyl chloride 
• 881009-83-2 2-methoxy-6-(trimethylsilyl)phenyltrifluoromethanesulfonate 

Relevant articles and documents

A Novel PPh3 Mediated One-Pot Method for Synthesis of 3-Aryl or Alkyl 1,2-Benzisoxazoles

A novel, efficient, and facile protocol has been developed for transforming 2-hydroxybenzonitriles and bromides into a range of 3-aryl or alkyl substituted 1,2-benzisoxazoles in good to excellent yields mediated by PPh3. The electronic and steric effects of bromides on the reaction are discussed. This is the first example to construct a C-C bond and heterocycle in a Barbier-Grignard-type reaction featuring easier recovery of PPh3 than a metallic catalyst in one step.