5409-51-8 Usage
Description
(1E)-5-(dimethylamino)-1-phenylpent-1-en-3-one hydrochloride is a chemical compound that serves as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is a hydrochloride salt of a ketone with a phenyl group and a dimethylamino group attached to the carbon chain. (1E)-5-(dimethylamino)-1-phenylpent-1-en-3-one hydrochloride is known for its versatile chemical reactivity and ability to participate in a variety of chemical reactions, making it a valuable building block for the production of various drugs. Its hydrochloride form enhances its stability and ease of handling in laboratory settings, underscoring its crucial role in the chemical synthesis of pharmaceuticals and other organic compounds.
Uses
Used in Pharmaceutical Synthesis:
(1E)-5-(dimethylamino)-1-phenylpent-1-en-3-one hydrochloride is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure and reactivity allow it to be incorporated into the molecular frameworks of a wide range of drugs, contributing to the development of new medications and therapeutic agents.
Used in Organic Chemistry Research:
In the field of organic chemistry, (1E)-5-(dimethylamino)-1-phenylpent-1-en-3-one hydrochloride is utilized as a versatile building block for the exploration of novel chemical reactions and the synthesis of complex organic molecules. Its ability to participate in multiple types of reactions makes it an invaluable tool for researchers in advancing the understanding of organic chemistry and developing new synthetic pathways.
Used in Drug Development:
(1E)-5-(dimethylamino)-1-phenylpent-1-en-3-one hydrochloride is employed as a component in drug development processes. Its incorporation into drug candidates can lead to the discovery of new pharmaceuticals with improved efficacy, safety, and pharmacokinetic properties. (1E)-5-(dimethylamino)-1-phenylpent-1-en-3-one hydrochloride's role in drug development is essential for the innovation of new treatments and medicines to address various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5409-51-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,0 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5409-51:
(6*5)+(5*4)+(4*0)+(3*9)+(2*5)+(1*1)=88
88 % 10 = 8
So 5409-51-8 is a valid CAS Registry Number.
5409-51-8Relevant articles and documents
Evaluation of alkylating and intercalating properties of mannich bases for cytotoxic activity
Istanbullu, Huseyin,Erzurumlu, Yalcin,Kirmizibayrak, Petek Ballar,Erciyas, Ercin
, p. 1096 - 1106 (2015/04/14)
A series of new "hybrid compounds", Mannich base derivatives of planar polycyclic/heterocyclic starting materials, was designed and synthesized. The structures of the compounds were confirmed by spectroscopic methods and elemental analysis. Cytotoxicity of compounds was investigated in three cancer cell lines (PC3, HeLa, and MCF7) and one non-tumoral cell line (293 HEK). We tested the DNA-intercalating capability of the molecules by ethidium bromide (EtBr) fluorescence displacement experiment. Compounds' alkylation potency was investigated via in vitro incubation test using 2-mercaptoethanol, a biomimetic nucleophile. The five of the compounds (7s, 9d, 10b, 11b, 12c) are reported for first time in the literature. Our results suggest that compound 9d has a biological activity close to the reference compound doxorubicin, an intercalating agent in clinical use.
Mannich Bases of 4-Phenyl-3-buten-2-one: A New Class of Antiherpes Agent
Edwards, M.L.,Ritter, H.W.,Stemerick, D.M.,Stewart, K.T.
, p. 431 - 436 (2007/10/02)
The morpholine Mannich base of 4-phenyl-3-buten-2-one was found to have activity in model infections of herpes simplex.The activity was essentially equivalent to that of disodium phosphonoacetate.This paper presents the biological activity and synthesis o
