5415-98-5

Basic information

• Product Name: N,N-DiMethyl-2-Methylene-β-alanine
• Synonyms: N,N-DiMethyl-2-Methylene-β-alanine;N,N-Dimethyl-2-methylene-2-alanine
• CAS NO: 5415-98-5
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.15704
• Product Categories: Miscellaneous Reagents
• Mol File: 5415-98-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 117.7-119.7 °C
• Boiling Point: 224.2 °C at 760 mmHg
• Flash Point: 89.4 °C
• Appearance: /
• Density: 1.038 g/cm³
• Vapor Pressure: 0.034mmHg at 25°C
• Refractive Index: 1.47
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly, Sonicated), Methanol (Slightly)
• PKA: 2.75±0.11(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: N,N-DiMethyl-2-Methylene-β-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DiMethyl-2-Methylene-β-alanine(5415-98-5)
• EPA Substance Registry System: N,N-DiMethyl-2-Methylene-β-alanine(5415-98-5)

Safety Data

• Hazardous Substances Data: 5415-98-5(Hazardous Substances Data)

Usage

Description

N,N-DiMethyl-2-Methylene-β-alanine is an organic compound with the molecular formula C7H11NO2. It is a derivative of β-alanine, an amino acid, with two methyl groups attached to the nitrogen atom and a methylene group (-CH2-) connected to the β-carbon atom. N,N-DiMethyl-2-Methylene-β-alanine is known for its potential applications in various fields due to its unique structural properties.

Uses

Used in Chemical Synthesis:
N,N-DiMethyl-2-Methylene-β-alanine is used as a building block in the synthesis of various organic compounds, particularly those with specific lipo/hydrophilic properties. Its unique structure allows for the creation of novel molecules with tailored characteristics, making it a valuable component in chemical research and development.
Used in Pyrimidine-based pH-sensitive Spin Probes:
N,N-DiMethyl-2-Methylene-β-alanine is used as a key component in the synthesis of pyrimidine-based pH-sensitive spin probes. These probes are essential tools in biochemistry and molecular biology for studying the pH levels and dynamics within cellular environments. N,N-DiMethyl-2-Methylene-β-alanine's structural properties enable the development of spin probes with diverse lipo/hydrophilic characteristics, which can be tailored to specific research applications and cellular targets.

InChI:InChI=1/C6H11NO2/c1-5(6(8)9)4-7(2)3/h1,4H2,2-3H3,(H,8,9)

Upstream product

• 50-00-0 formaldehyd 
• 141-82-2 malonic acid 
• 124-40-3 dimethyl amine 
• 1184-78-7 trimethylamine-N-oxide 
• 108-24-7 acetic anhydride 

Downstream Products

• 1092365-06-4 1-(3-(4-(3-chloro-2,4-difluorophenylamino)-7-methoxyquinazolin-6-yloxy)azetidin-1-yl)-2-((dimethylamino)methyl)prop-2-en-1-one 
• 1328623-76-2 N-((2-(4-amino-6-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)pyrimidin-5-yl)oxazol-4-yl)methyl)-2-(dimethylaminomethyl)acrylamide 
• 1328624-15-2 N-((2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)pyrimidin-5-yl)oxazol-4-yl)methyl)-2-dimethylaminomethylacrylamide 

Relevant articles and documents

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NOVEL PYRIMIDINE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS

The present invention provides a novel pyrimidine derivative or pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same, which can effectively inhibit the growth of cancer cells induced by the overexpression of EGFR incl

3-Pyrazolidinone derivatives

3-Pyrazolidinone compounds having a solubility of at least 12 grams/liter in an aqueous medium of pH 9 of the formula: STR1 wherein R is a mononuclear phenyl group having substituents in the 3, 4, or 5 positions with a total of no more than 4 non-metallic