54198-89-9 Usage
Description
5-Chloro-2-methylpyrimidine is an organic compound with the molecular formula C5H5ClN2. It is a derivative of pyrimidine, a heterocyclic aromatic organic compound that serves as a fundamental component in nucleic acids. The presence of a chlorine atom at the 5th position and a methyl group at the 2nd position distinguishes it from other pyrimidine derivatives.
Uses
Used in Pharmaceutical Industry:
5-Chloro-2-methylpyrimidine is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure allows it to be a key component in the synthesis of drugs targeting specific medical conditions.
Used in Antiviral Drug Synthesis:
In the context of antiviral drug development, 5-Chloro-2-methylpyrimidine is used as a reactant in the synthesis of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor. 5-Chloro-2-methylpyrimidine has potential applications in the treatment of chronic hepatitis C virus, offering a new avenue for therapeutic intervention against this viral infection.
Used in Chemical Research:
5-Chloro-2-methylpyrimidine also serves as a valuable compound in chemical research, particularly in the field of medicinal chemistry. Its unique properties and reactivity make it a useful building block for the design and synthesis of novel molecules with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 54198-89-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,1,9 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 54198-89:
(7*5)+(6*4)+(5*1)+(4*9)+(3*8)+(2*8)+(1*9)=149
149 % 10 = 9
So 54198-89-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H5ClN2/c1-4-7-2-5(6)3-8-4/h2-3H,1H3
54198-89-9Relevant articles and documents
Reactions of Halogenomethanes in the Vapour Phase. Part 5. The Reactions of Imidazolines, Anils, and 1-Methylimidazole with Chloroform at 550 deg C, and a Comparison with their Liquid-Phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base
Busby, Reginald E.,Khan, Mohammad A.,Khan, Mohammad R.,Parrick, John,Shaw, C. J. Granville
, p. 1431 - 1435 (2007/10/02)
The vapor-phase reactions of imidazolines and anils with chloroform at 550 deg C are compared with their liquid-phase reactions in the presence of hexachloroacetone and base or upon thermolysis with trichloroacetate ion.In the vapour-phase reactions imidazolines, unlike imidazoles, gave non-chlorinated pyrimidines, and 1-methyl-imidazole gave 2-cyanopyrrole and the four 3-chlorocyanopyridines.
