54239-39-3

Basic information

• Product Name: CIMBUTEROL
• Synonyms: CIMBUTEROL;Cimbuterol Solution, 100ppm
• CAS NO: 54239-39-3
• Molecular Formula: C₁₃H₁₉N₃O
• Molecular Weight: 233.30946
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 54239-39-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 189-191°C
• Boiling Point: 438.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
• PKA: 13.77±0.20(Predicted)
• CAS DataBase Reference: CIMBUTEROL(CAS DataBase Reference)
• NIST Chemistry Reference: CIMBUTEROL(54239-39-3)
• EPA Substance Registry System: CIMBUTEROL(54239-39-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 54239-39-3(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Upstream product

• 75-64-9 tert-butylamine 
• 88167-50-4 3-cyano-4-aminophenyl bromomethyl ketone 
• 54239-40-6 1-(4'-amino-3'-bromo-5'-cyano-phenyl)-2-tert-butylamino-ethanol 
• 99-92-3 p-aminobenzophenone 
• 56759-32-1 1-(4-amino-3-bromophenyl)-ethanone 
• 33720-71-7 4-amino-3-cyanoacetophenone 
• 56795-29-0 l-(4-amino-3-bromo-5-cyanophenyl)-2-tert-butylaminoethanol hydrochloride 
• 88167-51-5 2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile 
• 97760-78-6 4'-amino-3'-chloro-5'-cyano-acetophenone 
• 97776-06-2 4-acetyl-2-iodoaniline 
• 54239-60-0 4'-amino-3'-chloro-5'-cyano-2-tert.butylamino-acetophenone 

Relevant articles and documents

Phenylethanolamine β receptor agonist synthetic method

The invention discloses a phenylethanolamine β receptor agonist synthetic method, comprises the following steps: S1: the 4 - amino acetophenone dissolved in an organic solvent, with the electrophilic reagent occurs on the benzene ring substituted halogenated reaction, generating [...] intermediate; [...] intermediates in organic solvent or in water, under the catalysis of the metal catalyst with the cyanide reagent undergo nucleophilic substitution reaction, generating phenyl ketone intermediate; S2: phenyl ketone intermediates in organic solvent, with the copper bromide generating carbonyl α bromo reaction to produce α - bromoacetophenone intermediates; S3: α - bromoacetophenone intermediates in organic solvent with tert-butyl amine or isopropylamine reaction intermediates acetophenone amines; S4: acetophenone amine intermediates in organic solvent, with the reduction hydrogenation reagent react to generate the phenylethanolamine β receptor agonists; synthetic method of this invention a simple and highly efficient and cheap and easy to obtain, atom utilization is high, the synthetic product chemical purity is greater than 99%, to meet the detection requirements of the food safety.

Repartitioning Agents: 5--anthranilonitrile and Related Phenethanolamines; Agents for Promoting Growth, Increasing Muscle Accretion and Reducing Fat Deposition in Meat-producing Animals

A series of phenethanolamines related to clenbuterol was prepared and examined in mice for growth-promoting and fat-reducing activities.Several analogs were equipotent to clenbuterol.In chickens, 5-anthranilonitrile appeared to be more potent than clenbuterol with recpect to "repartitioning" activity, that is, the ability to redirect food energy from fat formation to muscle accretion.Based on this potency and low residue levels in edible tissues, this compound is in advanced stages of evaluation for commercial use in meat animals.

Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby

There is provided a method for enhancing the growth rate of meat-producing animals and/or improving the efficiency of feed utilization thereby, which involves, orally or parenterally, administering to said animals a growth-enhancing amount of a phenylethane compound or the acid addition salt thereof.